Human IL-1 alpha / IL-1F1 Protein, premium grade

Catalog number ILA-H5214-100ug

Discontinued

Price for ILA-H5214-100ug

Size / count 100 µg

This variant is discontinued and cannot be added to your cart.

About this product

Human IL-1 alpha Protein, premium grade (ILA-H5214) is expressed from human 293 cells (HEK293). It contains AA Ser 113 - Ala 271 (Accession # P01583-1).

Specifications

Catalog number: ILA-H5214-100ug
Size / count: 100 µg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Interleukin-1 alpha (IL1a) is also known as IL-1A, IL1, IL1-ALPHA,IL1F1,and is a cytokine of the interleukin-1 family. IL1a possesses a wide spectrum of metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. IL-1α is constitutively produced by epithelial cells. It is found in substantial amounts in normal human epidermis and is distributed in a 1:1 ratio between living epidermal cells and stratum corneum.The constitutive production of large amounts of IL-1α precursor by healthy epidermal keratinocytes interfere with the important role of IL-1α in immune responses, assuming skin as a barrier, which prevents the entry of pathogenic microorganisms into the body. In vitro, IL-1α possesses biological effect on cells in the picomolar to femtomolar range. In vivo, Shortly after an onset of an infection into organism, IL-1α activates a set of immune system response processes.
Specifications: This protein carries no "tag". The protein has a calculated MW of 18.0 kDa. The protein migrates as 22 kDa±3 kDa under reducing (R) condition, and 22 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Expression Region: Ser 113 - Ala 271
Host: HEK 293
Target: IL-1 alpha
Conjugation: Unconjugated
Tag: Native
Source: Human
Stability: -20°C to -70°C for 24 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin: 0.1 EU per μg
Purity: 95%
Format: Powder
Buffer: PBS, pH7.4
Additives: Trehalose
Molecular Weight: 18.0 kDa
Shipping Conditions: Room Temperature
Storage Conditions: -20°C

Frequently Asked Questions

What is the catalog number for Human IL-1 alpha / IL-1F1 Protein, premium grade?

The catalog number for Human IL-1 alpha / IL-1F1 Protein, premium grade is ILA-H5214-100ug.

Is Human IL-1 alpha / IL-1F1 Protein, premium grade in stock?

Human IL-1 alpha / IL-1F1 Protein, premium grade is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Human IL-1 alpha / IL-1F1 Protein, premium grade?

Human IL-1 alpha / IL-1F1 Protein, premium grade is manufactured by CRB.

What is the estimated delivery time for Human IL-1 alpha / IL-1F1 Protein, premium grade?

Estimated delivery time for Human IL-1 alpha / IL-1F1 Protein, premium grade is approximately 10 business day(s), depending on your location.

What is Human IL-1 alpha / IL-1F1 Protein, premium grade used for?

Human IL-1 alpha Protein, premium grade (ILA-H5214) is expressed from human 293 cells (HEK293). It contains AA Ser 113 - Ala 271 (Accession # P01583-1).

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.