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Product details

PML Protein Recombinant Rabbit Monoclonal Antibody [PSH02-68]

Catalog number HA721846

Price for HA721846

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Size / count 100 µL

About this product

Promyelocytic leukemia protein (PML) (also known as MYL, RNF71, PP8675 or TRIM19) is the protein product of the PML gene. PML protein is a tumor suppressor protein required for the assembly of a number of nuclear structures, called PML-nuclear bodies, which form amongst the chromatin of the cell nucleus. These nuclear bodies are present in mammalian nuclei, at about 1 to 30 per cell nucleus. PML-NBs are known to have a number of regulatory cellular functions, including involvement in programmed cell death, genome stability, antiviral effects and controlling cell division. PML mutation or loss, and the subsequent dysregulation of these processes, has been implicated in a variety of cancers.

Specifications

Catalog number
HA721846
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Acure promyelocytic leukemia, inducer of antibody MYL antibody Pml antibody PML_HUMAN antibody PP8675 antibody Probable transcription factor PML antibody Promyelocytic leukemia antibody Promyelocytic leukemia inducer of antibody Promyelocytic leukemia protein antibody Protein PML antibody RING finger protein 71 antibody RNF 71 antibody RNF71 antibody TRIM 19 antibody Tripartite motif protein TRIM19 antibody Tripartite motif-containing protein 19 antibody
Abbreviation
PML, MYL, PP8675, RNF71, TRIM19
Swiss Prot
P29590 Human,
Cellular Locus
Nucleus, Cytoplasm, PML body, nucleolus, Endoplasmic reticulum membrane, Early endosome membrane.
Host
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant protein within human PML Protein aa 1-600 / 882.
Isotype
IgG
Clone
PSH02-68
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Cell
Positive Control
HeLa cell lysate, HEK-293 cell lysate, K-562 cell lysate, A549 cell lysate, MDA-MB-231 cell lysate, A431 cell lysate, MDA-MB-231, human brain tissue, human breast carcinoma tissue, human breast tissue, human placenta tissue, human testis tissue, rat breast tissue.
Concentration
1 mg/mL
Dilution
WB: 1:5,000 ;IHC-P: 1:1,000 ;IF-Cell: 1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 98 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for PML Protein Recombinant Rabbit Monoclonal Antibody [PSH02-68]?

The catalog number for PML Protein Recombinant Rabbit Monoclonal Antibody [PSH02-68] is HA721846.

What sizes are available for PML Protein Recombinant Rabbit Monoclonal Antibody [PSH02-68]?

PML Protein Recombinant Rabbit Monoclonal Antibody [PSH02-68] is available in the following size(s): 100 µL.

Is PML Protein Recombinant Rabbit Monoclonal Antibody [PSH02-68] in stock?

PML Protein Recombinant Rabbit Monoclonal Antibody [PSH02-68] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PML Protein Recombinant Rabbit Monoclonal Antibody [PSH02-68] used for?

Promyelocytic leukemia protein (PML) (also known as MYL, RNF71, PP8675 or TRIM19) is the protein product of the PML gene. PML protein is a tumor suppressor protein required for the assembly of a number of nuclear structures, called PML-nuclear bodies, which form amongst the chromatin of the cell nuc

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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