IL-17A Polyclonal Antibody

Catalog number D-AB-10452L-01

Discontinued

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Size / count 25 µL

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Specifications

Catalog number: D-AB-10452L-01
Size / count: 25 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: IL17A, also named as IL-17, is a proinflammatory cytokine. IL-17, synthesized only by memory T cells and natural killer cells, has pleiotropic effects, mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO) . High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. The IL-17 receptor is a type I transmembrane protein, that is widely expressed on epithelial cells, fibroblasts, B and T cells, and monocytic cells. In psoriatic skin lesions, both Th17 cells and their downstream effector molecules, e.g. IL-17 and IL-22, are highly increased.
Abbreviation: IL-17A
UniProt: Q16552
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant Human IL-17A protein expressed by E.coli
Target: CTLA 8; CTLA-8; CTLA8; Cytotoxic T lymphocyte associated antigen 8; Cytotoxic T lymphocyte associated protein 8; Cytotoxic T lymphocyte associated serine esterase 8; Cytotoxic T-lymphocyte-associated antigen 8; IL 17A; IL-17; IL-17A; IL17; IL17; Il17a; Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8) ; Interleukin 17A; Interleukin-17A; Interleukin17; Interleukin17A; OTTHUMP00000016597; OTTMUSP00000046003
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: IHC
Field of Research: Cancer; Immunology
Purification: Antigen Affinity Purification
Concentration: 1 mg/mL
Dilution: IHC 1:300-1:600
Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Isotype: IgG

Frequently Asked Questions

What is the catalog number for IL-17A Polyclonal Antibody?

The catalog number for IL-17A Polyclonal Antibody is D-AB-10452L.

What sizes are available for IL-17A Polyclonal Antibody?

IL-17A Polyclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does IL-17A Polyclonal Antibody come in?

IL-17A Polyclonal Antibody is available in 2 different pack sizes.

Is IL-17A Polyclonal Antibody in stock?

IL-17A Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures IL-17A Polyclonal Antibody?

IL-17A Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for IL-17A Polyclonal Antibody?

Estimated delivery time for IL-17A Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for IL-17A Polyclonal Antibody?

The safety data sheet for IL-17A Polyclonal Antibody is available here: https://789.bio/eb/RxuHtH.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.