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![iFluor™ 488 Conjugated Beta Catenin Recombinant Rabbit Monoclonal Antibody [SA30-04] — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c90061270361ea82a61/imageurl/ha720182f.webp)
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Product details
Catalog number HA720182F
Price for HA720182F
Size / count 100 µL
Catenin beta-1, also known as beta-catenin (β-catenin), is a protein that in humans is encoded by the CTNNB1 gene. Beta-catenin is a dual function protein, involved in regulation and coordination of cell–cell adhesion and gene transcription. In humans, the CTNNB1 protein is encoded by the CTNNB1 gene. In Drosophila, the homologous protein is called armadillo. β-catenin is a subunit of the cadherin protein complex and acts as an intracellular signal transducer in the Wnt signaling pathway. Mutations and overexpression of β-catenin are associated with many cancers, including hepatocellular carcinoma, colorectal carcinoma, lung cancer, malignant breast tumors, ovarian and endometrial cancer. Alterations in the localization and expression levels of beta-catenin have been associated with various forms of heart disease, including dilated cardiomyopathy. β-catenin is regulated and destroyed by the beta-catenin destruction complex, and in particular by the adenomatous polyposis coli (APC) protein, encoded by the tumour-suppressing APC gene. Therefore, genetic mutation of the APC gene is also strongly linked to cancers, and in particular colorectal cancer resulting from familial adenomatous polyposis (FAP).
The catalog number for iFluor™ 488 Conjugated Beta Catenin Recombinant Rabbit Monoclonal Antibody [SA30-04] is HA720182F.
iFluor™ 488 Conjugated Beta Catenin Recombinant Rabbit Monoclonal Antibody [SA30-04] is available in the following size(s): 100 µL.
iFluor™ 488 Conjugated Beta Catenin Recombinant Rabbit Monoclonal Antibody [SA30-04] is currently made to order / not held in immediate stock. Contact us for lead time.
Catenin beta-1, also known as beta-catenin (β-catenin), is a protein that in humans is encoded by the CTNNB1 gene. Beta-catenin is a dual function protein, involved in regulation and coordination of cell–cell adhesion and gene transcription. In humans, the CTNNB1 protein is encoded by the CTNNB1 gen
Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.
We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.
Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.
