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![Lipoprotein a Recombinant Rabbit Monoclonal Antibody [JE39-47] — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea8148d/imageurl/ha722312.webp)
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Product details
Catalog number HA722312
Price for HA722312
Size / count 100 µL
Lp (a) is assembled at the hepatocyte cell membrane surface, which is similar to typical LDL particles. However, there are other possible locations of assembly. The particles mainly exist in plasma. Lp (a) contributes to the process of atherogenesis. The structure of apolipoprotein (a) is similar to plasminogen and tPA (tissue plasminogen activator) and it competes with plasminogen for its binding site, leading to reduced fibrinolysis. Also, because Lp (a) stimulates secretion of PAI-1, it leads to thrombogenesis. It also may enhance coagulation by inhibiting the function of tissue factor pathway inhibitor. Moreover, Lp (a) carries atherosclerosis-causing cholesterol and binds atherogenic pro-inflammatory oxidised phospholipids as a preferential carrier of oxidised phospholipids in human plasma, which attracts inflammatory cells to vessel walls and leads to smooth muscle cell proliferation. Moreover, Lp (a) also is hypothesised to be involved in wound healing and tissue repair by interacting with components of the vascular wall and extracellular matrix. Apo (a), a distinct feature of the Lp (a) particle, binds to immobilized fibronectin and endows Lp (a) with the serine-proteinase-type proteolytic activity.
The catalog number for Lipoprotein a Recombinant Rabbit Monoclonal Antibody [JE39-47] is HA722312.
Lipoprotein a Recombinant Rabbit Monoclonal Antibody [JE39-47] is available in the following size(s): 100 µL.
Lipoprotein a Recombinant Rabbit Monoclonal Antibody [JE39-47] is currently made to order / not held in immediate stock. Contact us for lead time.
Lp (a) is assembled at the hepatocyte cell membrane surface, which is similar to typical LDL particles. However, there are other possible locations of assembly. The particles mainly exist in plasma. Lp (a) contributes to the process of atherogenesis. The structure of apolipoprotein (a) is similar to
If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.
The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.
A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.
