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Product details

Phospho-Cytosolic Phospholipase A2 (S505) Recombinant Rabbit Monoclonal Antibody [PSH07-16]

Catalog number HA722804

Price for HA722804

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Size / count 100 µL

About this product

Cytosolic phospholipase A2 is an enzyme that in humans is encoded by the PLA2G4A gene. This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca2+ levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.

Specifications

Catalog number
HA722804
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Calcium dependent phospholipid binding protein antibody CPLA 2 antibody cPLA2 alpha antibody cPLA2 antibody Cytosolic phospholipase A2 antibody Cytosolic phospholipase A2 group IVA antibody Lysophospholipase antibody MGC126350 antibody PA24A_HUMAN antibody Phosphatidylcholine 2 acylhydrolase antibody Phosphatidylcholine 2-acylhydrolase antibody Phospholipase A2 group 4 A antibody Phospholipase A2 group IVA (cytosolic calcium dependent) antibody Phospholipase A2 group IVA antibody PhospholipaseA2 antibody PLA2G4 antibody pla2g4a antibody
Abbreviation
PLA2G4A, CPLA2, PLA2G4
Swiss Prot
P47712 Human, P47713 Mouse
Cellular Locus
Cytoplasm, Golgi apparatus membrane, Nucleus envelope.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic phospho-peptide corresponding to residues surrounding Ser505 of human cPLA2 aa 491-540.
Isotype
IgG
Clone
PSH07-16
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
HeLa cell lysate, RAW264.7 cell lysates.
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 85 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Phospho-Cytosolic Phospholipase A2 (S505) Recombinant Rabbit Monoclonal Antibody [PSH07-16]?

The catalog number for Phospho-Cytosolic Phospholipase A2 (S505) Recombinant Rabbit Monoclonal Antibody [PSH07-16] is HA722804.

What sizes are available for Phospho-Cytosolic Phospholipase A2 (S505) Recombinant Rabbit Monoclonal Antibody [PSH07-16]?

Phospho-Cytosolic Phospholipase A2 (S505) Recombinant Rabbit Monoclonal Antibody [PSH07-16] is available in the following size(s): 100 µL.

Is Phospho-Cytosolic Phospholipase A2 (S505) Recombinant Rabbit Monoclonal Antibody [PSH07-16] in stock?

Phospho-Cytosolic Phospholipase A2 (S505) Recombinant Rabbit Monoclonal Antibody [PSH07-16] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Phospho-Cytosolic Phospholipase A2 (S505) Recombinant Rabbit Monoclonal Antibody [PSH07-16] used for?

Cytosolic phospholipase A2 is an enzyme that in humans is encoded by the PLA2G4A gene. This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosa

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

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