Purified Anti-Human CD163 Antibody[MAC2-158]

Specifications

Catalog number

AN004800P-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Abbreviation

CD163

Gene ID

9332

UniProt

Q86VB7

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD163 protein

Target

GHI/; SCARI; CD163; M130; MM130; SCARI1; ED2 (rat) ; GHI/61; Hemoglobin/Haptoglobin Complex Receptor; macrophage-associated antigen; p155; RM3/1; GHI/61

Clonality

Monoclonal

Clone

MAC2-158

Conjugation

Unconjugated

Applications

FCM

Field of Research

Immunology; Cardiovascular

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Isotype

Mouse IgG1, κ