Purified Anti-Human CD14 Antibody[18D11]

Specifications

Catalog number

AN003610P-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 14 (CD14) is a member of the CD system. It takes its name from its inclusion in the CD molecule surface marker proteins. CD14 exists in two forms: a form anchored into the membrane or a soluble form. CD14 was found expressed in macrophages, neutrophil granulocyte and dendritic cells. The major function is to serve as a co-receptor (along with TLR4 and MD-2) for the bacterial lipopolysaccharide (LPS) and other pathogen-associated molecular patterns.

Abbreviation

CD14

Gene ID

929

UniProt

P08571

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD14 protein

Target

Monocyte differentiation antigen CD; CD14; soluble; CD14 antigen; CD14 molecule; monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; LPS R; CD 14; CD_antigen=CD14; LPS-R; membrane-bound form; Mo2; Monocyte differentiation antigen CD14 urinary form; Myeloid cell specific leucine rich glycoprotein

Clonality

Monoclonal

Clone

18D11

Conjugation

Unconjugated

Applications

FCM

Field of Research

Immunology; Stem Cells; Kits; Lysates; Other

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Isotype

Mouse IgG1, κ