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Product details

VPS11 Recombinant Rabbit Monoclonal Antibody [JE33-36]

Catalog number HA722447

Price for HA722447

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Size / count 100 µL

About this product

Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations. Required for fusion of endosomes and autophagosomes with lysosomes. Involved in cargo transport from early to late endosomes and required for the transition from early to late endosomes.

Specifications

Catalog number
HA722447
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
END1 antibody HGNC:14583 antibody hVPS11 antibody PEP5 antibody PP3476 antibody RING finger protein 108 antibody RNF108 antibody Vacuolar protein sorting 11 (yeast homolog) antibody Vacuolar protein sorting 11 (yeast) antibody Vacuolar protein sorting 11 homolog (S. cerevisiae) antibody Vacuolar protein sorting 11 homolog antibody Vacuolar protein sorting associated protein 11 homolog antibody Vacuolar protein sorting protein 11 antibody Vacuolar protein sorting-associated protein 11 homolog antibody vps11 antibody VPS11_HUMAN antibody
Abbreviation
Vacuolar protein sorting-associated protein 11 homolog hVPS11 RING finger protein 108 VPS11 RNF108 PP3476
Swiss Prot
Q9H270 Human
Cellular Locus
Cytoplasmic vesicle. Endosome. Lysosome. Membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human VPS11 aa aa10-44 / 941.
Isotype
IgG
Clone
JE33-36
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
HEK-293 cell lysate, Jurkat cell lysate, HeLa cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 108 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for VPS11 Recombinant Rabbit Monoclonal Antibody [JE33-36]?

The catalog number for VPS11 Recombinant Rabbit Monoclonal Antibody [JE33-36] is HA722447.

What sizes are available for VPS11 Recombinant Rabbit Monoclonal Antibody [JE33-36]?

VPS11 Recombinant Rabbit Monoclonal Antibody [JE33-36] is available in the following size(s): 100 µL.

Is VPS11 Recombinant Rabbit Monoclonal Antibody [JE33-36] in stock?

VPS11 Recombinant Rabbit Monoclonal Antibody [JE33-36] is currently made to order / not held in immediate stock. Contact us for lead time.

What is VPS11 Recombinant Rabbit Monoclonal Antibody [JE33-36] used for?

Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 e

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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