Human IL-2 Receptor alpha Recombinant Rabbit Monoclonal Antibody [PSH05-66] - BSA and Azide free (Detector)

Catalog number HA722386

Price for HA722386

Size / count 100 µL

About this product

Interleukin-2 receptor alpha chain (also called CD25) is the human protein encoded by the IL2RA gene. The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolysis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is currently unknown. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes. IL2RA is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, mastocytosis and tumor infiltrating lymphocytes. It functions as the receptor for HTLV-1 and is consequently expressed on neoplastic cells in adult T cell lymphoma/leukemia. Its soluble form, called sIL-2R may be elevated in these diseases and is occasionally used to track disease progression. Infection by the protozoan Trypanosoma cruzi causes Chagas disease, characterized by a reduction in the amount of IL2RA expressed on the surface of immune cells. This leads to chronic immune suppression, becoming increasingly severe over the course of many years and ultimately resulting in death if left untreated.

Specifications

Catalog number: HA722386
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Interleukin 2 receptor alpha chain antibody CD25 antibody CD25 antigen antibody IDDM10 antibody IL 2 receptor alpha subunit antibody IL-2 receptor subunit alpha antibody IL-2-RA antibody IL-2R subunit alpha antibody IL2 RA antibody IL2 Receptor alpha antibody IL2-RA antibody IL2R antibody IL2R, alpha chain antibody IL2RA antibody IL2RA_HUMAN antibody IMD41 antibody Interleukin 2 receptor alpha antibody Interleukin 2 receptor antibody Interleukin-2 receptor subunit alpha antibody p55 antibody t-cell growth factor receptor antibody TAC antibody TAC antigen antibody TCGFR antibody
Abbreviation: Interleukin-2 receptor subunit alpha IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA TAC antigen p55 CD25 IL2RA
Swiss Prot: P01589 Human
Cellular Locus: Membrane.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within human IL-2 Receptor alpha aa 22-240 (Extracellular).
Isotype: IgG
Clone: PSH05-66
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: ELISA (Det)
Positive Control: Recombinant standard Human IL2RA protein (HA210771).
Concentration: 1 mg/mL
Dilution: ELISA (Det): Use at an assay dependent concentration. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH05-65] to Human IL2RA (Capture) (HA722385) and recombinant standard Human IL2RA protein (HA210771). The reference range value is 8.2-2000pg/ml.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4).
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Human IL-2 Receptor alpha Recombinant Rabbit Monoclonal Antibody [PSH05-66] - BSA and Azide free (Detector)?

The catalog number for Human IL-2 Receptor alpha Recombinant Rabbit Monoclonal Antibody [PSH05-66] - BSA and Azide free (Detector) is HA722386.

What sizes are available for Human IL-2 Receptor alpha Recombinant Rabbit Monoclonal Antibody [PSH05-66] - BSA and Azide free (Detector)?

Human IL-2 Receptor alpha Recombinant Rabbit Monoclonal Antibody [PSH05-66] - BSA and Azide free (Detector) is available in the following size(s): 100 µL.

Is Human IL-2 Receptor alpha Recombinant Rabbit Monoclonal Antibody [PSH05-66] - BSA and Azide free (Detector) in stock?

Human IL-2 Receptor alpha Recombinant Rabbit Monoclonal Antibody [PSH05-66] - BSA and Azide free (Detector) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Human IL-2 Receptor alpha Recombinant Rabbit Monoclonal Antibody [PSH05-66] - BSA and Azide free (Detector) used for?

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.