CD79a Recombinant Rabbit Monoclonal Antibody [JE32-14]

About this product

Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B-cells.

Specifications

Catalog number

HA722896

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

B lymphocyte-specific MB1 protein antibody B-cell antigen receptor complex-associated protein alpha chain antibody CD 79a antibody CD79a antibody CD79a antigen (immunoglobulin-associated alpha) antibody CD79A antigen antibody CD79a molecule, immunoglobulin-associated alpha antibody CD79A_HUMAN antibody Ig alpha antibody Ig-alpha antibody IGA antibody IgM-alpha antibody Immunoglobulin-associated alpha antibody Ly54 antibody MB-1 membrane glycoprotein antibody MB1 antibody Membrane-bound immunoglobulin-associated protein antibody Surface IgM-associated protein antibody

Abbreviation

B-cell antigen receptor complex-associated protein alpha chain Ig-alpha MB-1 membrane glycoprotein Membrane-bound immunoglobulin-associated protein Surface IgM-associated protein CD79a

Swiss Prot

P11912 Human

Cellular Locus

Cell membrane

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide.

Isotype

IgG

Clone

JE32-14

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Cell

Positive Control

Ramos cell lysate, Daudi cell lysate, Raji cell lysate, Daudi, human colon tissue, human lung cancer tissue, human spleenr tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:200-1:1,000 ;IF-Cell: 1:50

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 25 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes