Purified Anti-Human CD52 Antibody[5F7]

Specifications

Catalog number

AN002860P-01

Size / count

25 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD52, also known as Cambridge pathology antigen 1 (CAMPATH-1), is a 25-29 kD glycoprotein containing a large N-linked carbohydrate moiety. The actual molecule of CD52 is only 8-9 kD. It is expressed in the male reproductive tract and on virtually all lymphocytes (T and B cells), as well as macrophages/monocytes, eosinophils, and red cells. CD52 is thought to play a role in carrying and orienting carbohydrates. CD52 is a potent target for complement-mediated lysis and antibody-mediated cellular cytotoxicity and has been used as a depletion target for chronic lymphocytic leukemia (CLL) /lymphoma and immunosuppression.

Abbreviation

CD52

Gene ID

1043

UniProt

P31358

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD52 protein

Target

CDW; Epididymal secretory protein E; Human epididymis-specific protein; CAMPATH; CAMPATH-1; CAMPATH-1 antigen; CD52 antigen; CD52 molecule; Epididymal secretory protein E5; HEL-S-171mP; Human epididymis-specific protein 5; CDW52; HE5; CD52; HE5

Clonality

Monoclonal

Clone

5F7

Conjugation

Unconjugated

Applications

FCM

Field of Research

Immunology

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Isotype

Mouse IgG3, κ