Phospho-eNOS (S1177) Recombinant Rabbit Monoclonal Antibody [PS01-10]

Catalog number HA721188

Price for HA721188

Size / count 100 µL

About this product

Endothelial NOS (eNOS), also known as nitric oxide synthase 3 (NOS3) or constitutive NOS (cNOS), is an enzyme that in humans is encoded by the NOS3 gene located in the 7q35-7q36 region of chromosome 7. This enzyme is one of three isoforms that synthesize nitric oxide (NO), a small gaseous and lipophilic molecule that participates in several biological processes. The other isoforms include neuronal nitric oxide synthase (nNOS), which is constitutively expressed in specific neurons of the brain[8] and inducible nitric oxide synthase (iNOS), whose expression is typically induced in inflammatory diseases. eNOS is primarily responsible for the generation of NO in the vascular endothelium, a monolayer of flat cells lining the interior surface of blood vessels, at the interface between circulating blood in the lumen and the remainder of the vessel wall. NO produced by eNOS in the vascular endothelium plays crucial roles in regulating vascular tone, cellular proliferation, leukocyte adhesion, and platelet aggregation. Therefore, a functional eNOS is essential for a healthy cardiovascular system.

Specifications

Catalog number: HA721188
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: cNOS antibody Constitutive NOS antibody EC NOS antibody EC-NOS antibody ecNOS antibody Endothelial nitric oxidase synthase antibody Endothelial nitric oxide synthase antibody Endothelial nitric oxide synthase 3 antibody Endothelial NOS antibody eNOS antibody Nitric oxide synthase 3 (endothelial cell) antibody Nitric oxide synthase 3 antibody Nitric oxide synthase 3 endothelial cell antibody Nitric oxide synthase endothelial antibody Nitric oxide synthase, endothelial antibody NOS 3 antibody NOS III antibody NOS type III antibody NOS3 antibody NOS3_HUMAN antibody NOSIII antibody
Abbreviation: NOS3
Swiss Prot: P29474 Human
Cellular Locus: Cell membrane, Membrane, caveola, Cytoplasm, cytoskeleton, Golgi apparatus.
Host: Rabbit
Species Reactivity: Human, Dog, Mouse, Rat
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding Ser1177 of human eNOS.
Isotype: IgG
Clone: PS01-10
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: HAEC serum starved then treated with 100nM Insulin for 1 hour cell lysate, human placenta tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 133 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Phospho-eNOS (S1177) Recombinant Rabbit Monoclonal Antibody [PS01-10]?

The catalog number for Phospho-eNOS (S1177) Recombinant Rabbit Monoclonal Antibody [PS01-10] is HA721188.

What sizes are available for Phospho-eNOS (S1177) Recombinant Rabbit Monoclonal Antibody [PS01-10]?

Phospho-eNOS (S1177) Recombinant Rabbit Monoclonal Antibody [PS01-10] is available in the following size(s): 100 µL.

Is Phospho-eNOS (S1177) Recombinant Rabbit Monoclonal Antibody [PS01-10] in stock?

Phospho-eNOS (S1177) Recombinant Rabbit Monoclonal Antibody [PS01-10] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Phospho-eNOS (S1177) Recombinant Rabbit Monoclonal Antibody [PS01-10] used for?

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.