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Product details

TIRAP Recombinant Rabbit Monoclonal Antibody [JE46-35]

Catalog number HA722001

Price for HA722001

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Size / count 100 µL

About this product

TIRAP (TIR domain containing adaptor protein) is an adapter molecule associated with toll-like receptors. The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.

Specifications

Catalog number
HA722001
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Adapter protein wyatt antibody FLJ42305 antibody MAL antibody MyD88 adapter like protein antibody TIR domain containing adapter protein antibody Toll interleukin 1 receptor (TIR) domain containing adaptor protein antibody Toll interleukin 1 receptor domain containing adapter protein antibody Toll like receptor adaptor protein antibody Wyatt antibody
Abbreviation
TIRAP, MAL
Swiss Prot
P58753 Human, Q99JY1 Mouse
Cellular Locus
Cytoplasm, Cell membrane, Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within Human TIRAP aa 1-50 / 221.
Isotype
IgG
Clone
JE46-35
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
HeLa cell lysate, U-2 OS cell lysate, RAW264.7 cell lysate, mouse liver tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 24 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for TIRAP Recombinant Rabbit Monoclonal Antibody [JE46-35]?

The catalog number for TIRAP Recombinant Rabbit Monoclonal Antibody [JE46-35] is HA722001.

What sizes are available for TIRAP Recombinant Rabbit Monoclonal Antibody [JE46-35]?

TIRAP Recombinant Rabbit Monoclonal Antibody [JE46-35] is available in the following size(s): 100 µL.

Is TIRAP Recombinant Rabbit Monoclonal Antibody [JE46-35] in stock?

TIRAP Recombinant Rabbit Monoclonal Antibody [JE46-35] is currently made to order / not held in immediate stock. Contact us for lead time.

What is TIRAP Recombinant Rabbit Monoclonal Antibody [JE46-35] used for?

TIRAP (TIR domain containing adaptor protein) is an adapter molecule associated with toll-like receptors. The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-ass

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

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