UBE2C Recombinant Rabbit Monoclonal Antibody [JE38-67]

Catalog number HA722454

Price for HA722454

Size / count 100 µL

About this product

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit. Component of the APC/C complex, composed of at least 14 distinct subunits that assemble into a complex of at least 19 chains with a combined molecular mass of around 1.2 MDa. Within this complex, directly interacts with ANAPC2.

Specifications

Catalog number: HA722454
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Cyclin selective ubiquitin carrier protein antibody dJ447F3.2 antibody Mitotic specific ubiquitin conjugating enzyme antibody UB E2C antibody UBCH 10 antibody UbcH10 antibody UBE 2C antibody Ube2c antibody UBE2C_HUMAN antibody Ubiquitin carrier protein C antibody Ubiquitin carrier protein E2 C antibody Ubiquitin carrier protein E2C antibody Ubiquitin conjugating enzyme E2 C antibody Ubiquitin conjugating enzyme E2C antibody Ubiquitin protein ligase C antibody Ubiquitin-conjugating enzyme E2 C antibody Ubiquitin-protein ligase C antibody
Abbreviation: Ubiquitin-conjugating enzyme E2 C (E3-independent) E2 ubiquitin-conjugating enzyme C E2 ubiquitin-conjugating enzyme C UbcH10 Ubiquitin carrier protein C Ubiquitin-protein ligase C UBE2C UBCH10
Swiss Prot: O00762 Human
Cellular Locus: Cytosol. Nucleoplasm.Nucleus.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within Human UBE2C aa 80-179 / 179.
Isotype: IgG
Clone: JE38-67
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB
Positive Control: HeLa cell lysate, HEK-293 cell lysate, THP-1 cell lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 20 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for UBE2C Recombinant Rabbit Monoclonal Antibody [JE38-67]?

The catalog number for UBE2C Recombinant Rabbit Monoclonal Antibody [JE38-67] is HA722454.

What sizes are available for UBE2C Recombinant Rabbit Monoclonal Antibody [JE38-67]?

UBE2C Recombinant Rabbit Monoclonal Antibody [JE38-67] is available in the following size(s): 100 µL.

Is UBE2C Recombinant Rabbit Monoclonal Antibody [JE38-67] in stock?

UBE2C Recombinant Rabbit Monoclonal Antibody [JE38-67] is currently made to order / not held in immediate stock. Contact us for lead time.

What is UBE2C Recombinant Rabbit Monoclonal Antibody [JE38-67] used for?

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.