DPP4/CD26 Polyclonal Antibody

Catalog number AN006840L-01

Discontinued

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Price for AN006840L-01

Size / count 25 µL

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Specifications

Catalog number: AN006840L-01
Size / count: 25 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the N-terminus of polypeptides, such as chemokines, neuropeptides, and peptide hormones. The enzyme is a type II transmembrane glycoprotein, expressed on the surface of many cell types. It is also present in serum and other body fluids in a truncated form (sCD26/DPPIV) . The soluble CD26 (sCD26) as a tumour marker for the detection of colorectal cancer (CRC) and advanced adenomas. As both a regulatory enzyme and a signalling factor, DPP4 has been evaluated and described in many studies. DPP4 inhibition results in increased blood concentration of the incretin hormones glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) . This causes an increase in glucose-dependent stimulation, resulting in a lowering of blood glucose levels. Recent studies have shown that DPP4 inhibitors can induce a significant reduction in glycosylated haemoglobin (HbA (1c) ) levels, either as monotherapy or as a combination with other antidiabetic agents. Research has also demonstrated that DPP4 inhibitors portray a very low risk of hypoglycaemia development, and are a new pharmacological class of drugs for treating Type 2 diabetes.
Abbreviation: DPP4
UniProt: P28843
Host: Rabbit
Reactivity: Mouse; Rat
Immunogen: Recombinant Mouse DPP4/CD26 protein expressed by Mammalian
Target: DPP; Adenosine Deaminase Complexing Protein; ADCP; ADABP; ADCP2; Adenosine Deaminase Complexing Protein 2; DPPIV; TP103; Cd26; Dpp4; Dipeptidyl peptidase IV (DPP IV) ; THAM
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB
Purification: Antigen Affinity Purification
Concentration: 1 mg/mL
Dilution: WB 1:1000-1:2000
Buffer: PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 87 kDa
Observed Molecular Weight: 110 kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for DPP4/CD26 Polyclonal Antibody?

The catalog number for DPP4/CD26 Polyclonal Antibody is AN006840L.

What sizes are available for DPP4/CD26 Polyclonal Antibody?

DPP4/CD26 Polyclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does DPP4/CD26 Polyclonal Antibody come in?

DPP4/CD26 Polyclonal Antibody is available in 2 different pack sizes.

Is DPP4/CD26 Polyclonal Antibody in stock?

DPP4/CD26 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures DPP4/CD26 Polyclonal Antibody?

DPP4/CD26 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for DPP4/CD26 Polyclonal Antibody?

Estimated delivery time for DPP4/CD26 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for DPP4/CD26 Polyclonal Antibody?

The safety data sheet for DPP4/CD26 Polyclonal Antibody is available here: https://789.bio/eb/deHVq1.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.