Kaiso Recombinant Rabbit Monoclonal Antibody [JE38-42]

Catalog number HA722275

Price for HA722275

Size / count 100 µL

About this product

Transcriptional regulator Kaiso is a protein that in humans is encoded by the ZBTB33 gene. This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-α2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified.

Specifications

Catalog number: HA722275
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Kaiso antibody Kaiso protein antibody Kaiso transcription factor antibody KAISO_HUMAN antibody Transcriptional regulator Kaiso antibody ZBTB 33 antibody Zbtb33 antibody Zinc finger and BTB domain containing 33 antibody Zinc finger and BTB domain-containing protein 33 antibody Zinc finger transcription factor Kaiso antibody ZNF 348 antibody ZNF Kaiso antibody ZNF348 antibody
Abbreviation: ZBTB33, KAISO, ZNF348
Swiss Prot: Q86T24 Human,
Cellular Locus: Nucleus, Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Rat
Immunogen: Synthetic peptide within Human Kaiso aa 600-700.
Isotype: IgG
Clone: JE38-42
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, FC
Positive Control: MCF7 cell lysate, HeLa cell lysate, HCT 116 cell lysate, C6 cell lysate, HeLa, C6.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IF-Cell: 1:100 ;FC: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 74 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Kaiso Recombinant Rabbit Monoclonal Antibody [JE38-42]?

The catalog number for Kaiso Recombinant Rabbit Monoclonal Antibody [JE38-42] is HA722275.

What sizes are available for Kaiso Recombinant Rabbit Monoclonal Antibody [JE38-42]?

Kaiso Recombinant Rabbit Monoclonal Antibody [JE38-42] is available in the following size(s): 100 µL.

Is Kaiso Recombinant Rabbit Monoclonal Antibody [JE38-42] in stock?

Kaiso Recombinant Rabbit Monoclonal Antibody [JE38-42] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Kaiso Recombinant Rabbit Monoclonal Antibody [JE38-42] used for?

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.