Product details

CD22 Polyclonal Antibody

Catalog number D-AB-10188L-01

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Price for D-AB-10188L-01

Size / count 25 µL

Specifications

Catalog number: D-AB-10188L-01
Size / count: 25 µL
Dry ice: No
Hazardous: No
Discontinued: No
Background: CD22, also known as Siglec-2 (sialic acid binding Ig-like lectin 2) or BL-CAM (B-lymphocyte cell adhesion molecule), is a 130-140 kDa, B-cell restricted, type I transmembrane glycoprotein belonging to the immunoglobulin gene superfamily. The expression of CD22 is developmentally regulated. It is expressed at low levels in the cytoplasm of pro-B and pre-B cells and present on the cell surface only at mature stages of B-cell differentiation. Cell surface expression is lost during terminal differentiation into plasma cell and after B-cell activation. CD22 is an inhibitory receptor for B-cell receptor (BCR) signalling, preferentially binds to alpha-2,6-linked sialic acid and mediates B-cell B-cell interactions. It plays a crucial role in activation and differentiation of the B-cell.
Abbreviation: CD22
UniProt: P20273
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant Human CD22 protein expressed by E.coli
Target: B cell receptor CD22 precursor; B lymphocyte cell adhesion molecule; BL CAM; CD 22; CD22 antigen; CD22 molecule; Lectin 2; Leu14; Lyb8; MGC130020; sialic acid binding Ig like lectin 2; SIGLEC 2; T cell surface antigen Leu 14
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Field of Research: Cancer; Immunology; Stem Cells
Purification: Antigen Affinity Purification
Concentration: 1 mg/mL
Dilution: WB 1:500-1:1000; IHC 1:200-1:400
Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 95kDa
Observed Molecular Weight: 135kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for CD22 Polyclonal Antibody?

The catalog number for CD22 Polyclonal Antibody is D-AB-10188L.

What sizes are available for CD22 Polyclonal Antibody?

CD22 Polyclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does CD22 Polyclonal Antibody come in?

CD22 Polyclonal Antibody is available in 2 different pack sizes.

Is CD22 Polyclonal Antibody in stock?

CD22 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD22 Polyclonal Antibody?

CD22 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for CD22 Polyclonal Antibody?

Estimated delivery time for CD22 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD22 Polyclonal Antibody?

The safety data sheet for CD22 Polyclonal Antibody is available here: https://789.bio/eb/tW94VS.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.