AF/LE Purified Anti-Human CD62L Antibody[DREG56]

Specifications

Catalog number

E-AB-F10510-01

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naive T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naive, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.

Abbreviation

CD62L

Gene ID

6402

UniProt

P14151

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD62L protein

Target

Leukocyte adhesion molecule; Leukocyte surface antigen Leu; Leukocyte-endothelial cell adhesion molecule; LECAM; LAM; LEU; SELL; CD62L; LAM1; LECAM1; LEU8; LNHR; LSEL; LYAM1; PLNHR; TQ1; CD62 antigen-like family member L; CD62antigen-likefamilymemberL; gp90-MEL; LAM-1; Leu-8; Leukocyte adhesion molecule 1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; L-selectin; Ly22; Ly-22; Lyam-1; Lymph node homing receptor; Lymphnodehomingreceptor;6&apos- sulfated Lewis X-X; LECAM-1; LAM-1

Clonality

Monoclonal

Clone

DREG56

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Cardiovascular; Immunology; Stem Cells

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

66

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Isotype

Mouse IgG1, κ