Cdc6 Recombinant Rabbit Monoclonal Antibody [JE59-52]

Catalog number HA721304

Price for HA721304

Size / count 100 µL

About this product

Cdc6, or cell division cycle 6, is a protein in eukaryotic cells. CDC6 is an ATP binding protein and a member of the pre-replicative complex (pre-RC) together with the origin recognition complex (ORC), Cdt1 and the MCM complex (containing MCM2-7p). CDC6 assembles after ORC in an ATP dependent manner and is required for loading MCM proteins onto the DNA. It is thought that the CDC6-Cdt1 complex uses ATP hydrolysis to thread DNA through the central hole of the MCM doughnut. Mutations in the binding motif of CDC6 strongly suggest that ATP binding and hydrolysis is essential for its function. The minimal requirement for DNA binding has been mapped within its 47-amino acid sequence. Furthermore, Cdc6 indirectly inhibits activation of the p34cdc2/CDC28 M phase kinase, thus nuclear division is suppressed.

Specifications

Catalog number: HA721304
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Cdc 18L antibody Cdc 6 antibody CDC18 (cell division cycle 18, S.pombe, homolog) like antibody CDC18 (S.pombe) antibody Cdc18 related protein antibody CDC18 (S.pombe) antibody Cdc18-related protein antibody Cdc18L antibody cdc6 antibody CDC6 cell division cycle 6 homolog antibody CDC6 related protein antibody CDC6-related protein antibody CDC6_HUMAN antibody Cdc6p antibody CELL CYCLE CONTROLLER CDC6 antibody Cell division control protein 6 antibody Cell division control protein 6 homolog antibody Cell division cycle 6 homolog (S. cerevisiae) antibody Cell division cycle 6 homolog antibody Cell division cycle 6, S. cerevisiae, homolog of antibody HsCDC 6 antibody HsCDC18 antibody HsCDC6 antibody p62 antibody p62 (cdc 6) antibody p62 (cdc6) antibody
Abbreviation: HsCdc18, HsCDC6, CDC6
Swiss Prot: Q99741 Human
Cellular Locus: Nucleus, Cytoplasm.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser54 of Human Cdc6 aa 41-90 / 560.
Isotype: IgG
Clone: JE59-52
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: Hela cell lysate, HepG2 cell lysate, human striated muscle tissue, human testis muscle tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500 ;IHC-P: 1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 63 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Cdc6 Recombinant Rabbit Monoclonal Antibody [JE59-52]?

The catalog number for Cdc6 Recombinant Rabbit Monoclonal Antibody [JE59-52] is HA721304.

What sizes are available for Cdc6 Recombinant Rabbit Monoclonal Antibody [JE59-52]?

Cdc6 Recombinant Rabbit Monoclonal Antibody [JE59-52] is available in the following size(s): 100 µL.

Is Cdc6 Recombinant Rabbit Monoclonal Antibody [JE59-52] in stock?

Cdc6 Recombinant Rabbit Monoclonal Antibody [JE59-52] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cdc6 Recombinant Rabbit Monoclonal Antibody [JE59-52] used for?

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.