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Product details

UBA3 Recombinant Mouse Monoclonal Antibody [1C10-5-5-R]

Catalog number HA601234

Price for HA601234

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Size / count 100 µL

About this product

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Specifications

Catalog number
HA601234
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
DKFZp566J164 antibody EC 6.3.2. antibody hUba3 antibody MGC22384 antibody NEDD8 activating enzyme E1 catalytic subunit antibody NEDD8 activating enzyme E1C antibody Nedd8 activating enzyme hUba3 antibody NEDD8-activating enzyme E1 catalytic subunit antibody NEDD8-activating enzyme E1C antibody uba3 antibody UBA3 ubiquitin activating enzyme E1 homolog antibody UBA3_HUMAN antibody UBE1C antibody Ubiquitin activating enzyme 3 antibody Ubiquitin activating enzyme E1C antibody Ubiquitin-activating enzyme 3 antibody Ubiquitin-activating enzyme E1C antibody Ubiquitin-like modifier-activating enzyme 3 antibody
Abbreviation
UBA3
Swiss Prot
Q8TBC4 Human, Q8C878 Mouse, Q99MI7 Rat
Cellular Locus
Cytosol, nucleus, cytoplasm.
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human UBA3 aa 220-424 / 463.
Isotype
IgG1
Clone
1C10-5-5-R
Conjugation
Non-conjugated
Type
Recombinant Mouse monoclonal Antibody
Applications
WB, IHC-P
Positive Control
HeLa cell lysate, 293T cell lysate, HepG2 cell lysate, K-562 cell lysate, HL-60 cell lysate, Jurkat cell lysate, mouse brain tissue lysate, rat brain tissue lysate, human brain tissue, mouse brain tissue, rat brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:500-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 52 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for UBA3 Recombinant Mouse Monoclonal Antibody [1C10-5-5-R]?

The catalog number for UBA3 Recombinant Mouse Monoclonal Antibody [1C10-5-5-R] is HA601234.

What sizes are available for UBA3 Recombinant Mouse Monoclonal Antibody [1C10-5-5-R]?

UBA3 Recombinant Mouse Monoclonal Antibody [1C10-5-5-R] is available in the following size(s): 100 µL.

Is UBA3 Recombinant Mouse Monoclonal Antibody [1C10-5-5-R] in stock?

UBA3 Recombinant Mouse Monoclonal Antibody [1C10-5-5-R] is currently made to order / not held in immediate stock. Contact us for lead time.

What is UBA3 Recombinant Mouse Monoclonal Antibody [1C10-5-5-R] used for?

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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