Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 (AS35)

Catalog number SAD-S35-1mg

Discontinued

Price for SAD-S35-1mg

Size / count 1 mg

This variant is discontinued and cannot be added to your cart.

About this product

Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 (AS35) (SAD-S35) is isolated from a SARS-CoV-2 infected patient and is recombinantly produced from human 293 cells (HEK293). This antibody recognizes the SARS-CoV-2 Spike Protein RBD domain and inhibits the interaction between SARS-CoV-2 RBD and ACE2 with an IC50 of 1.47 μg/mL using SARS-CoV-2 Inhibitor Screening Kit.<strong>Pseudovirus assay shows that this antibody has potent neutralizing activity against pseudovirus bearing SARS-CoV-2 Spike protein.</strong>

Specifications

Catalog number: SAD-S35-1mg
Size / count: 1 mg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
CAS Number: 9007-83-4
Host: HEK 293
Origin Species: Human
Target: Spike RBD
Conjugation: Unconjugated
Tag: Human IgG1 | Human Kappa
Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower._x000D_Please avoid repeated freeze-thaw cycles.
Purity: 95%
Bioactivity: Immobilized SARS-CoV-2 S1 protein, His Tag at 2 μg/mL (100 μL/well) can bind Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 (AS35) (Cat. No. SAD-S35) with a linear range of 0.2-1.95 ng/mL (QC tested).
Format: Powder
Buffer: PBS, pH7.4
Additives: Trehalose
Shipping Conditions: Room Temperature
Storage Conditions: -20°C

Frequently Asked Questions

What is the catalog number for Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 (AS35)?

The catalog number for Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 (AS35) is SAD-S35-1mg.

Is Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 (AS35) in stock?

Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 (AS35) is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 (AS35)?

Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 (AS35) is manufactured by CRB.

What is the estimated delivery time for Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 (AS35)?

Estimated delivery time for Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 (AS35) is approximately 10 business day(s), depending on your location.

What is Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Human IgG1 (AS35) used for?

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.