TBPL1 Recombinant Rabbit Monoclonal Antibody [JE30-79]

About this product

TATA box-binding protein-like protein 1 is a protein that in humans is encoded by the TBPL1 gene. Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.

Specifications

Catalog number

HA722426

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

TATA box-binding protein-like 1 TBP-like 1 21 kDa TBP-like protein Second TBP of unique DNA protein (STUD) TATA box-binding protein-related factor 2 (TBP-related factor 2) TBP-like factor TBP-related protein TBPL1 TLF TLP TLP21 TRF2 TRP

Abbreviation

TBPL1, TLF, TLP, TLP21, TRF2, TRP

Swiss Prot

P62380 Human

Cellular Locus

Cytoplasm, Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within Human TBPL1 aa 87-186 / 186.

Isotype

IgG

Clone

JE30-79

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Tissue, FC, IP

Positive Control

HeLa cell lysate, 293T cell lysate, mouse testis tissue lysate, rat testis tissue lysate, human testis tissue, mouse testis tissue, rat testis tissue, 293T.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:1,000 ;IF-Tissue: 1:200 ;FC: 1:1,000 ;IP: 1-2μg/sample

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 21 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes