Dopamine beta Hydroxylase Recombinant Rabbit Monoclonal Antibody [JE43-56]

Catalog number HA722558

Price for HA722558

Size / count 100 µL

About this product

Dopamine beta-hydroxylase (DBH), also known as dopamine beta-monooxygenase, is an enzyme (EC 1.14.17.1) that in humans is encoded by the DBH gene. Dopamine is converted to norepinephrine by the enzyme dopamine β-hydroxylase; ascorbic acid serves as a cofactor. The three substrates of the enzyme are dopamine, vitamin C (ascorbate), and O2. The products are norepinephrine, dehydroascorbate, and H2O. DBH is a 290 kDa copper-containing oxygenase consisting of four identical subunits, and its activity requires ascorbate as a cofactor. It is the only enzyme involved in the synthesis of small-molecule neurotransmitters that is membrane-bound, making norepinephrine the only known transmitter synthesized inside vesicles. It is expressed in noradrenergic neurons of the central nervous system (i.e. locus coeruleus) and peripheral nervous systems (i.e. sympathetic ganglia), as well as in chromaffin cells of the adrenal medulla.

Specifications

Catalog number: HA722558
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: dbh antibody DBM antibody Dopamine beta hydroxylase antibody Dopamine beta monooxygenase antibody Dopamine beta-hydroxylase (dopamine beta-monooxygenase) antibody Dopamine beta-monooxygenase antibody DOPO_HUMAN antibody OTTHUMP00000022501 antibody Soluble dopamine beta-hydroxylase antibody
Abbreviation: DBH
Swiss Prot: P09172 Human
Cellular Locus: Cytoplasmic vesicle, secretory vesicle membrane, secretory vesicle, chromaffin granule membrane.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within
Isotype: IgG
Clone: JE43-56
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB
Positive Control: SH-SY5Y cell lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 69 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Dopamine beta Hydroxylase Recombinant Rabbit Monoclonal Antibody [JE43-56]?

The catalog number for Dopamine beta Hydroxylase Recombinant Rabbit Monoclonal Antibody [JE43-56] is HA722558.

What sizes are available for Dopamine beta Hydroxylase Recombinant Rabbit Monoclonal Antibody [JE43-56]?

Dopamine beta Hydroxylase Recombinant Rabbit Monoclonal Antibody [JE43-56] is available in the following size(s): 100 µL.

Is Dopamine beta Hydroxylase Recombinant Rabbit Monoclonal Antibody [JE43-56] in stock?

Dopamine beta Hydroxylase Recombinant Rabbit Monoclonal Antibody [JE43-56] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Dopamine beta Hydroxylase Recombinant Rabbit Monoclonal Antibody [JE43-56] used for?

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.