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![KLKB1 Recombinant Rabbit Monoclonal Antibody [JE31-29] — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c90061270361ea82bdd/imageurl/ha721397.webp)
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Product details
Catalog number HA721397
Price for HA721397
Size / count 100 µL
Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulfide bond. The heavy chain originates from the amino-terminal end of the zymogen and contains 4 tandem repeats of 90 or 91 amino acids. Each repeat harbors a novel structure called the apple domain. The heavy chain is required for the surface-dependent pro-coagulant activity of plasma kallikrein. The light chain contains the active site or catalytic domain of the enzyme and is homologous to the trypsin family of serine proteases. Plasma prekallikrein deficiency causes a prolonged activated partial thromboplastin time in patients. Kallikrein and prekallikrein have been shown to interact with High-molecular-weight kininogen.
The catalog number for KLKB1 Recombinant Rabbit Monoclonal Antibody [JE31-29] is HA721397.
KLKB1 Recombinant Rabbit Monoclonal Antibody [JE31-29] is available in the following size(s): 100 µL.
KLKB1 Recombinant Rabbit Monoclonal Antibody [JE31-29] is currently made to order / not held in immediate stock. Contact us for lead time.
Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma ka
Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.
Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.
Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.
