COMP Mouse Monoclonal Antibody [A10H2]

Catalog number HA601354

Price for HA601354

Size / count 100 µL

About this product

Cartilage oligomeric matrix protein (COMP), also known as thrombospondin-5, is an extracellular matrix (ECM) protein primarily present in cartilage. In humans it is encoded by the COMP gene. The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfide bonds. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudoachondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). COMP is a marker of cartilage turnover. It is present in high quantities in fibrotic scars and systemic sclerosis, and it appears to have a role in vascular wall remodeling.

Specifications

Catalog number: HA601354
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple) antibody Cartilage oligomeric matrix protein antibody Cartilage oligomeric matrix protein precursor antibody COMP antibody COMP_HUMAN antibody EDM 1 antibody EDM1 antibody EPD 1 antibody EPD1 antibody Epiphyseal dysplasia 1 antibody Epiphyseal dysplasia 1 multiple antibody Epiphyseal dysplasia multiple 1 antibody MED antibody MGC13181 antibody MGC149768 antibody PSACH antibody pseudoachondroplasia (epiphyseal dysplasia 1, multiple) antibody Pseudoachondroplasia antibody THBS 5 antibody THBS5 antibody Thrombospondin 5 antibody Thrombospondin-5 antibody Thrombospondin5 antibody TSP5 antibody
Abbreviation: COMP
Swiss Prot: P49747 Human, Q9R0G6 Mouse, P35444 Rat
Cellular Locus: Secreted, extracellular space, extracellular matrix.
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within human COMP aa 321-370.
Isotype: IgG1
Clone: A10H2
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P
Positive Control: Mouse articular cartilage tissue lysate, Rat articular cartilage tissue lysate, mouse cartilage tissue, rat cartilage tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:400
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 83 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for COMP Mouse Monoclonal Antibody [A10H2]?

The catalog number for COMP Mouse Monoclonal Antibody [A10H2] is HA601354.

What sizes are available for COMP Mouse Monoclonal Antibody [A10H2]?

COMP Mouse Monoclonal Antibody [A10H2] is available in the following size(s): 100 µL.

Is COMP Mouse Monoclonal Antibody [A10H2] in stock?

COMP Mouse Monoclonal Antibody [A10H2] is currently made to order / not held in immediate stock. Contact us for lead time.

What is COMP Mouse Monoclonal Antibody [A10H2] used for?

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.