Pannexin 1 Recombinant Rabbit Monoclonal Antibody [JE38-97]

Catalog number HA721629

Price for HA721629

Size / count 100 µL

About this product

Pannexin 1 is a protein in humans that is encoded by the PANX1 gene. The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties. Truncating mutations in this gene have been shown to promote breast cancer metastasis to the lungs by allowing cancer cells to survive mechanical stretch in the microcirculation. Disruptions of this gene have been associated to melanoma tumor progression. Pannexin 1 is also an important component of membrane channels involved in the formation of thin plasma membrane extensions called apoptopodia and beaded apoptopodia during apoptosis.

Specifications

Catalog number: HA721629
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: innexin antibody MRS1 antibody Pannexin 1 antibody Pannexin-1 antibody Panx1 antibody PANX1_HUMAN antibody PX1 antibody UNQ2529 antibody
Abbreviation: PANX1, MRS1
Swiss Prot: Q96RD7 Human, Q9JIP4 Mouse, P60570 Rat
Cellular Locus: Cell membrane, Cell junction, gap junction, Endoplasmic reticulum membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human Pannexin 1 aa 377-426 / 426.
Isotype: IgG
Clone: JE38-97
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IF-Cell
Positive Control: K-562 cell lysate, 293T cell lysate, U-87 MG cell lysate, Jurkat cell lysate, SH-SY5Y cell lysate, NIH/3T3 cell lysate, C2C12 cell lysate, rat brain tissue lysate, mouse brain tissue lysate, human kidney tissue, mouse brain tissue, rat brain tissue, 293T.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:1,000 ;IF-Cell: 1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 24 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Pannexin 1 Recombinant Rabbit Monoclonal Antibody [JE38-97]?

The catalog number for Pannexin 1 Recombinant Rabbit Monoclonal Antibody [JE38-97] is HA721629.

What sizes are available for Pannexin 1 Recombinant Rabbit Monoclonal Antibody [JE38-97]?

Pannexin 1 Recombinant Rabbit Monoclonal Antibody [JE38-97] is available in the following size(s): 100 µL.

Is Pannexin 1 Recombinant Rabbit Monoclonal Antibody [JE38-97] in stock?

Pannexin 1 Recombinant Rabbit Monoclonal Antibody [JE38-97] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Pannexin 1 Recombinant Rabbit Monoclonal Antibody [JE38-97] used for?

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.