SARS-CoV-2 (COVID-19) S1 protein (HV69-70del), His Tag

Catalog number S1N-C52Hd-1mg

Discontinued

Price for S1N-C52Hd-1mg

Size / count 1 mg

This variant is discontinued and cannot be added to your cart.

About this product

SARS-CoV-2 S1 protein (HV69-70del), His Tag (S1N-C52Hd) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Arg 685 (Accession # QHD43416.1 (HV69-70del)). HV69-70 deletion was identified in the SARS-CoV-2 Alpha variant (Pango lineage: B.1.1.7; other names: 20I/501Y.V1 or VOC 202012/01).

Specifications

Catalog number: S1N-C52Hd-1mg
Size / count: 1 mg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Specifications: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 76.7 kDa. The protein migrates as 100-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expression Region: Val 16 - Arg 685
Host: HEK 293
Target: Spike S1
Conjugation: Unconjugated
Tag: C-10×His
Source: SARS-CoV-2
Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin: 1.0 EU per μg
Purity: 90%
Bioactivity: Immobilized SARS-CoV-2 S1 protein (HV69-70del), His Tag (Cat. No. S1N-C52Hd) at 2 μg/mL (100 μL/well) can bind Human ACE2, Fc Tag (Cat. No. AC2-H5257) with a linear range of 0.1-2 ng/mL (QC tested).
Format: Powder
Buffer: PBS, pH7.4
Additives: Trehalose
Molecular Weight: 76.7 kDa
Shipping Conditions: Room Temperature
Storage Conditions: -20°C

Frequently Asked Questions

What is the catalog number for SARS-CoV-2 (COVID-19) S1 protein (HV69-70del), His Tag?

The catalog number for SARS-CoV-2 (COVID-19) S1 protein (HV69-70del), His Tag is S1N-C52Hd-1mg.

Is SARS-CoV-2 (COVID-19) S1 protein (HV69-70del), His Tag in stock?

SARS-CoV-2 (COVID-19) S1 protein (HV69-70del), His Tag is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SARS-CoV-2 (COVID-19) S1 protein (HV69-70del), His Tag?

SARS-CoV-2 (COVID-19) S1 protein (HV69-70del), His Tag is manufactured by CRB.

What is the estimated delivery time for SARS-CoV-2 (COVID-19) S1 protein (HV69-70del), His Tag?

Estimated delivery time for SARS-CoV-2 (COVID-19) S1 protein (HV69-70del), His Tag is approximately 10 business day(s), depending on your location.

What is SARS-CoV-2 (COVID-19) S1 protein (HV69-70del), His Tag used for?

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.