HMGB1 Rabbit Polyclonal Antibody — image 1 of 6

Product details

HMGB1 Rabbit Polyclonal Antibody

Catalog number ER0913

Price for ER0913

Size / count 100 µL

About this product

Like the histones, HMGB1, also known as high-mobility group protein 1 (HMG-1) is among the most important chromatin proteins. In the nucleus HMGB1 interacts with nucleosomes, transcription factors, and histones. This nuclear protein organizes the DNA and regulates transcription. After binding, HMGB1 bends DNA, which facilitates the binding of other proteins. HMGB1 is secreted by immune cells through leaderless secretory pathway. Activated macrophages and monocytes secrete HMGB1 as a cytokine mediator of Inflammation. In recent research, HMGB1 has been reported as a novel biomarker for human ovarian cancer.

Specifications

Catalog number: ER0913
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Amphoterin antibody Chromosomal protein, nonhistone, HMG1 antibody DKFZp686A04236 antibody High mobility group 1 antibody High mobility group box 1 antibody High mobility group protein 1 antibody High mobility group protein B1 antibody high-mobility group (nonhistone chromosomal) protein 1 antibody HMG-1 antibody HMG1 antibody HMG3 antibody HMGB 1 antibody HMGB1 antibody HMGB1_HUMAN antibody NONHISTONE CHROMOSOMAL PROTEIN HMG1 antibody SBP 1 antibody Sulfoglucuronyl carbohydrate binding protein antibody
Abbreviation: HMG-1
Swiss Prot: P09429 Human
Cellular Locus: Nucleus, Cell membrane, Cytoplasm, Secreted.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within human HMGB1 aa 71-126.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: Wild-type Raw264.7 whole cell lysate, HepG2 cell lysate, MCF-7 cell lysate, F9 cell lysate, A549 cell lysate, Hela, NIH/3T3, mouse kidney tissue, mouse stomach tissue, mouse brain tissue, human stomach carcinoma tissue, human tonsil tissue,
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000;IF-Cell: 1:200;IHC-P: 1:200;FC: 1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 25 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for HMGB1 Rabbit Polyclonal Antibody?

The catalog number for HMGB1 Rabbit Polyclonal Antibody is ER0913.

What sizes are available for HMGB1 Rabbit Polyclonal Antibody?

HMGB1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is HMGB1 Rabbit Polyclonal Antibody in stock?

HMGB1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is HMGB1 Rabbit Polyclonal Antibody used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.