SLC40A1 Mouse Monoclonal Antibody [A10A1]

Catalog number HA601178

Price for HA601178

Size / count 100 µL

About this product

Ferroportin-1, also known as solute carrier family 40 member 1 (SLC40A1) or iron-regulated transporter 1 (IREG1), is a protein that in humans is encoded by the SLC40A1 gene, and is part of the Ferroportin (Fpn) Family. Ferroportin is a transmembrane protein that transports iron from the inside of a cell to the outside of the cell. Ferroportin is the only known iron exporter. After dietary iron is absorbed into the cells of the small intestine, ferroportin allows that iron to be transported out of those cells and into the bloodstream. Fpn also mediates the efflux of iron recycled from macrophages resident in the spleen and liver. Ferroportin is regulated by hepcidin, a hormone produced by the liver; hepcidin binds to Fpn and limits its iron-efflux activity, thereby reducing iron delivery to the blood plasma. Therefore, the interaction between Fpn and hepcidin controls systemic iron homeostasis.

Specifications

Catalog number: HA601178
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Ferroportin 1 antibody Ferroportin antibody Ferroportin-1 antibody FPN1 antibody HFE4 antibody IREG1 antibody iron regulated gene 1 antibody Iron regulated transporter 1 antibody Iron-regulated transporter 1 antibody MST079 antibody MSTP079 antibody MTP1 antibody putative ferroportin 1 variant IIIA antibody putative ferroportin 1 variant IIIB antibody S40A1_HUMAN antibody SLC11A3 antibody SLC11A3, formerly antibody SLC40A1 antibody solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3 antibody solute carrier family 11 (proton-coupled divalent metal ion transporters), member 3, formerly antibody solute carrier family 40 (iron-regulated transporter), member 1 antibody Solute carrier family 40 member 1 antibody
Abbreviation: SLC40A1, FPN, FPN1, IREG1, SLC11A3, MSTP079
Swiss Prot: Q9NP59 Human
Cellular Locus: Cell membrane, Basolateral cell membrane.
Host: Mouse
Species Reactivity: Human
Immunogen: Synthetic peptide within human SLC40A1 aa 257-306 / 571.
Isotype: IgG1
Clone: A10A1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB
Positive Control: HEK-293 cell lysate, HepG2 cell lysate, A375 cell lysate, NCCIT cell lysate, Caco-2 cell lysate, SW480 cell lysate.
Concentration: 0.87 mg/mL
Dilution: WB: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 63 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for SLC40A1 Mouse Monoclonal Antibody [A10A1]?

The catalog number for SLC40A1 Mouse Monoclonal Antibody [A10A1] is HA601178.

What sizes are available for SLC40A1 Mouse Monoclonal Antibody [A10A1]?

SLC40A1 Mouse Monoclonal Antibody [A10A1] is available in the following size(s): 100 µL.

Is SLC40A1 Mouse Monoclonal Antibody [A10A1] in stock?

SLC40A1 Mouse Monoclonal Antibody [A10A1] is currently made to order / not held in immediate stock. Contact us for lead time.

What is SLC40A1 Mouse Monoclonal Antibody [A10A1] used for?

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.