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Product details

HEC1 Recombinant Rabbit Monoclonal Antibody [JE31-10]

Catalog number HA721395

Price for HA721395

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Size / count 100 µL

About this product

Kinetochore protein NDC80 homolog is a protein that in humans is encoded by the NDC80 gene. Ndc80 is one of the proteins of outer kinetochore. It forms a heterotetramer with proteins NUF2, SPC25, and SPC24. This protein complex has microtubule-binding domains. HEC is one of several proteins involved in spindle checkpoint signaling. This surveillance mechanism assures correct segregation of chromosomes during cell division by detecting unaligned chromosomes and causing prometaphase arrest until the proper bipolar attachment of chromosomes is achieved. NDC80 has been shown to interact with MIS12, NEK2 and PSMC2.v

Specifications

Catalog number
HA721395
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
from Entrez Gene ; antibody HEC antibody Highly expressed in cancer antibody Highly expressed in cancer protein antibody Highly expressed in cancer rich in leucine heptad repeats antibody HsHec1 antibody hsNDC80 antibody Kinetochore associated 2 antibody Kinetochore associated protein 2 antibody Kinetochore protein Hec1 antibody Kinetochore protein NDC80 homolog antibody Kinetochore-associated protein 2 antibody KNTC2 antibody ndc80 antibody NDC80 homolog kinetochore complex component antibody NDC80 kinetochore complex component homolog antibody NDC80, S. cerevisiae, homolog of antibody NDC80_HUMAN antibody Retinoblastoma associated protein HEC antibody Retinoblastoma-associated protein HEC antibody TID3 antibody
Abbreviation
NDC80, HEC, HEC1, KNTC2
Swiss Prot
O14777 Human
Cellular Locus
Nucleus, Chromosome, centromere, kinetochore.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within Human HEC1 aa 593-642 / 642.
Isotype
IgG
Clone
JE31-10
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
K-562 cell lysate, U-2 OS cell lysate, HeLa cell lysate, HEK-293 cell lysate, Jurkat cell lysate, MCF7 cell lysate, HepG2 cell lysate, LO2 cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 74 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for HEC1 Recombinant Rabbit Monoclonal Antibody [JE31-10]?

The catalog number for HEC1 Recombinant Rabbit Monoclonal Antibody [JE31-10] is HA721395.

What sizes are available for HEC1 Recombinant Rabbit Monoclonal Antibody [JE31-10]?

HEC1 Recombinant Rabbit Monoclonal Antibody [JE31-10] is available in the following size(s): 100 µL.

Is HEC1 Recombinant Rabbit Monoclonal Antibody [JE31-10] in stock?

HEC1 Recombinant Rabbit Monoclonal Antibody [JE31-10] is currently made to order / not held in immediate stock. Contact us for lead time.

What is HEC1 Recombinant Rabbit Monoclonal Antibody [JE31-10] used for?

Kinetochore protein NDC80 homolog is a protein that in humans is encoded by the NDC80 gene. Ndc80 is one of the proteins of outer kinetochore. It forms a heterotetramer with proteins NUF2, SPC25, and SPC24. This protein complex has microtubule-binding domains. HEC is one of several proteins involved

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

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