SLUG Recombinant Rabbit Monoclonal Antibody [PSH07-40]

Catalog number HA722828

Price for HA722828

Size / count 100 µL

About this product

This gene encodes a member of the Snail superfamily of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. It regulates differentiation and migration of neural crest cells along with other genes (e.g. FOXD3, SOX9 and SOX10, BMPs) in embryonic life. Mutations in this gene may be associated with sporadic cases of neural tube defects. SNAI2 downregulates expression of E-cadherin in premigratory neural crest cells; thus, SNAI2 induces tightly bound epithelial cells to break into a loose mesenchymal phenotype, allowing gastrulation of mesoderm in the developing embryo. Structurally similar to anti-apoptotic Ces-1 in C. elegans, SLUG is a negative regulator of productive cell death in the developing embryo and adults.

Specifications

Catalog number: HA722828
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: MGC10182 antibody Neural crest transcription factor Slug antibody Protein snail homolog 2 antibody Slug (chicken homolog) zinc finger protein antibody Slug homolog zinc finger protein antibody Slug zinc finger protein antibody SLUGH antibody SLUGH 1 antibody SLUGH1 antibody SNAI 2 antibody Snai2 antibody SNAI2_HUMAN antibody Snail 2 antibody Snail homolog 2 antibody Snail2 antibody WS 2D antibody WS2D antibody Zinc finger protein SLUG antibody Zinc finger protein SNAI2 antibody
Abbreviation: SNAI2, SLUG, SLUGH
Swiss Prot: O43623 Human
Cellular Locus: Nucleus, Cytoplasm.
Host: Rabbit
Species Reactivity: Human
Immunogen: Recombinant protein within human SLUG aa 1-150.
Isotype: IgG
Clone: PSH07-40
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell
Positive Control: U-87 MG cell lysate, SK-MEL-28 cell lysate, SK-MEL-28.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IF-Cell: 1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 30 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for SLUG Recombinant Rabbit Monoclonal Antibody [PSH07-40]?

The catalog number for SLUG Recombinant Rabbit Monoclonal Antibody [PSH07-40] is HA722828.

What sizes are available for SLUG Recombinant Rabbit Monoclonal Antibody [PSH07-40]?

SLUG Recombinant Rabbit Monoclonal Antibody [PSH07-40] is available in the following size(s): 100 µL.

Is SLUG Recombinant Rabbit Monoclonal Antibody [PSH07-40] in stock?

SLUG Recombinant Rabbit Monoclonal Antibody [PSH07-40] is currently made to order / not held in immediate stock. Contact us for lead time.

What is SLUG Recombinant Rabbit Monoclonal Antibody [PSH07-40] used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.