Biotinylated Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM130) (MALS verified)

About this product

The Mouse monoclonal antibody is produced from a hybridoma resulting from fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Spike RBD F(ab')₂.

Specifications

Catalog number

SPD-BM227-200ug

Size / count

200 µg

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

CAS Number

9007-83-4

Host

HEK 293

Origin Species

Mouse

Target

Spike RBD

Conjugation

Biotin-labeled

Tag

Human IgG1 & Avi | Human Kappa

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower._x000D_Please avoid repeated freeze-thaw cycles.

Purity

95%

Bioactivity

Immobilized SARS-CoV-2 S protein RBD, His Tag(Cat. No. SPD-C52H3) at 2 μg/mL (100 μL/well) can bind Biotinylated Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM130) (Cat. No. SPD-BM227) with a linear range of 0.195-25ng/mL (QC tested)

Format

Powder

Buffer

PBS, pH7.3

Additives

Trehalose

Shipping Conditions

Room Temperature

Storage Conditions

-20°C