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Product details

Bulk Anti-Human CD11b (ICRF44) Antibody

Catalog number ICH1007-50mg

Price for ICH1007-50mg

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Size / count 50 mg

Specifications

Catalog number
ICH1007-50mg
Size / count
50 mg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Anti-CD11b may be used to study lymphocyte subsets in flow cytometry and in cell adhesion research (Mac-1). The antibody may be used to stain tissue sections which have been acetone fixed and frozen.
CAS Number
9007-83-4
Specifications
Anti-CD11b In Vivo Antibody - Low Endotoxin (44) recognizes Human CD11b. Anti-Human CD11b recognizes the alpha subunit of the CD11b/CD18 complex, an alpha/Beta heterodimeric surface glycoprotein on human leukocytes (Mr 165-170 kDa). The CD11b/CD18 antigen belongs to the B2 integrin family. Other names include Mac-1, Cr3, MO-1 and C3bi receptor. The CD11b molecule functions as a receptor for C3bi complement, clotting factor X, fibrinogen and ICAM-1.
Product Name Alternative
Integrin alpha-M,ITGAM, ICR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, CR3A
UniProt
P11215
Host
Mouse
Species Reactivity
Human
Target
CD11b
Isotype
IgG1
Clone
ICRF44
Applications
Flow Cytometry, Western Blot, IHC (Frozen), Immunoprecipitation
Purification Method
This monoclonal antibody was purified using Protein A
Concentration
≥ 2.0 mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and analyzed by silver stain.
Buffer
ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions
Blue ice
Storage Conditions
Anti-CD11b In Vivo Antibody - Low Endotoxin (44) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution
The CD11b antigen is expressed on approximately 30% of human peripheral blood lymphocytes, most natural killer lymphocytes, circulating monocytes, granulocytes, a subset of T-cells and subsets of macrophages.
Aggregation
Aggregation level ≤ 5%
Applications Notes
Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control
https://www.ichor.bio/product/Mouse-IgG1-Isotype-Control-for-In-Vivo-Low-Endotoxin-HKSP-ICH2247

Frequently Asked Questions

What is the catalog number for Bulk Anti-Human CD11b (ICRF44) Antibody?

The catalog number for Bulk Anti-Human CD11b (ICRF44) Antibody is ICH1007-50mg.

What sizes are available for Bulk Anti-Human CD11b (ICRF44) Antibody?

Bulk Anti-Human CD11b (ICRF44) Antibody is available in the following size(s): 50 mg.

Is Bulk Anti-Human CD11b (ICRF44) Antibody in stock?

Bulk Anti-Human CD11b (ICRF44) Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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