Bulk Anti-Human CD16 (3G8) Antibody

Catalog number ICH1010-5mg

Price for ICH1010-5mg

Size / count 5 mg

Specifications

Catalog number: ICH1010-5mg
Size / count: 5 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: CD16 is known as low affinity IgG receptor III (Fc gamma RIII) and is expressed as two distinct forms (CD16a and CD16b). CD16a (Fc gamma RIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. CD16b (Fc gamma RIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils.
CAS Number: 9007-83-4
Specifications: Anti-CD16 In Vivo Antibody - Low Endotoxin (3G8) recognizes an epitope on Human CD16
Product Name Alternative: FCGR3A, Fc-gamma RIII, FcRIII
UniProt: P08637
Host: Mouse
Species Reactivity: Human
Target: CD16
Isotype: IgG1 Kappa
Clone: 3G8
Applications: IHC (Frozen), Flow Cytometry, Immunoprecipitation, Blocking, CyTOF
Purification Method: This monoclonal antibody was purified using Protein A
Concentration: ≥ 2.0 mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE and HPLC
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: Anti-CD16 In Vivo Antibody - Low Endotoxin (3G8) is stable when stored at 2-8°C.
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, without BSA or sodium azide added.
Antigen Distribution: CD16 is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans.
Aggregation: Aggregation level ≤ 5%
Applications Notes: Flow Cytometry: For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume. Blocking: Clone 3G8 antibody blocks neutrophil phagocytosis and stimulates NK cell proliferation. Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control: https://www.ichor.bio/product/Mouse-IgG1-Isotype-Control-for-In-Vivo-Low-Endotoxin-HKSP-ICH2247

Frequently Asked Questions

What is the catalog number for Bulk Anti-Human CD16 (3G8) Antibody?

The catalog number for Bulk Anti-Human CD16 (3G8) Antibody is ICH1010-5mg.

What sizes are available for Bulk Anti-Human CD16 (3G8) Antibody?

Bulk Anti-Human CD16 (3G8) Antibody is available in the following size(s): 5 mg.

Is Bulk Anti-Human CD16 (3G8) Antibody in stock?

Bulk Anti-Human CD16 (3G8) Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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