- Catalog number
- ICH1017-50mg
- Size / count
- 50 mg
- Dry ice
- No
- Hazardous
- No
- Discontinued
- No
- Background
- L-selectin, also known as CD62L, is a cell adhesion molecule consisting of a large, highly glycosylated, extracellular domain found on leukocytes. It belongs to the selectin family of proteins, which recognise sialylated carbohydrate groups. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via the high endothelial venules. L-selectin is an effective marker for separating lymphoid progenitors from myeloid progenitors and hematopoietic stem cells in bone marrow.
- CAS Number
- 9007-83-4
- Specifications
- Anti-CD62L In Vivo Antibody - Low Endotoxin (DREG56) recognizes an epitope on Human CD62L
- Product Name Alternative
- L-selectin, SELL, Leukocyte adhesion molecule 1, LAM-11
Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LECAM1, Lymph node homing receptor1, TQ12, gp90-MEL, LNHR, LYAM1
- UniProt
- P14151
- Host
- Mouse
- Species Reactivity
- Human
- Target
- CD62L
- Isotype
- IgG1
- Clone
- DREG56
- Applications
- Western Blot, Blocking, Functional Assays, Flow Cytometry
- Purification Method
- This monoclonal antibody was purified using Protein A
- Concentration
- 1.0 mg/mL
- Endotoxin
- ≤ 1.0 EU/mg as determined by the LAL method
- Purity
- >95% by SDS-PAGE and HPLC
- Buffer
- ICH3001-100mL
ICH3002-100mL
ICH3003-100mL
- Shipping Conditions
- Blue ice
- Storage Conditions
- Anti-CD62L In Vivo Antibody - Low Endotoxin (DREG56) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
- Formulation
- 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
- Antigen Distribution
- Majority of B cells, na��ve T cells, subset of memory T and NK cells, monocytes, granulocytes, thymocytes
- Aggregation
- Aggregation level ≤ 5%
- Applications Notes
- Each investigator should determine their own optimal working dilution for specific applications.
- Isotype Control
- https://www.ichor.bio/product/Mouse-IgG1-Isotype-Control-for-In-Vivo-Low-Endotoxin-HKSP-ICH2247