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Product details

Bulk Anti-Human HLA-DR (L243) Antibody

Catalog number ICH1026-50mg

Price for ICH1026-50mg

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Size / count 50 mg

Specifications

Catalog number
ICH1026-50mg
Size / count
50 mg
Dry ice
No
Hazardous
No
Discontinued
No
Background
HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD (heavy) chain & a 27 kD (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, and dendritic cells. HLA-DR is critical for efficient peptide presentation to CD4+ T cells. Clone L243 binds a conformational epitope on HLA-DRalpha which depends on the correct folding of the Aβ heterodimer.
CAS Number
9007-83-4
Specifications
Anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) recognizes/reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross-react with HLA-DP and HLA-DQ
Product Name Alternative
Major Histocompatibility Class II, MHC class II, HLA-DR Monomorphic
Host
Mouse
Species Reactivity
Human
Target
HLA-DR
Isotype
IgG2a
Clone
L243
Applications
Western Blot, Blocking, Flow Cytometry, Immunoprecipitation, CyTOF, IHC (Frozen)
Purification Method
This monoclonal antibody was purified using Protein A
Concentration
1.0 mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Buffer
ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions
Blue ice
Storage Conditions
Anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) is stable for at least four (4) weeks when stored at 2-8°C. For long-term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Formulation
No carrier proteins or preservatives added in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4.
Antigen Distribution
The HLA-DR antigen is present on B-lymphocytes, activated T-lymphocytes and activated natural killer (NK) lymphocytes. This antigen is also expressed on monocytes, macrophages, human progenitor cells and B-cell lymphomas.
Aggregation
Aggregation level ≤ 5%
Applications Notes
Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control
https://www.ichor.bio/product/Mouse-IgG2a-In-Vivo-Isotype-Control-Low-Endotoxin-C1.18.4-ICH2245

Frequently Asked Questions

What is the catalog number for Bulk Anti-Human HLA-DR (L243) Antibody?

The catalog number for Bulk Anti-Human HLA-DR (L243) Antibody is ICH1026-50mg.

What sizes are available for Bulk Anti-Human HLA-DR (L243) Antibody?

Bulk Anti-Human HLA-DR (L243) Antibody is available in the following size(s): 50 mg.

Is Bulk Anti-Human HLA-DR (L243) Antibody in stock?

Bulk Anti-Human HLA-DR (L243) Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

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