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Product details

Anti-ICAM-1 (15.2) In Vivo Antibody - Ultra-Low Endotoxin

Catalog number ICH1027UL-5mg

Price for ICH1027UL-5mg

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Size / count 5 mg

Specifications

Catalog number
ICH1027UL-5mg
Size / count
5 mg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is constitutively present on endothelial cells, but its expression is increased by proinflammatory cytokines. ICAM-1 is a marker of endothelial dysfunction leading to damaging vascular disorders, in umbilical and placental vascular tissue of gestational pregnancies.
CAS Number
9007-83-4
Specifications
Mouse anti-Human Inter-Cellular Adhesion Molecule 1 (ICAM-1) (Clone 15.2) - Ultra-Low Endotoxin recognizes an epitope on Human ICAM-1
Product Name Alternative
Intercellular adhesion molecule 1, ICAM1, Major group rhinovirus receptor, CD54
UniProt
P05362
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Target
ICAM-1
Isotype
IgG1
Clone
15.2
Applications
IHC (FFPE), Flow Cytometry, Immunoprecipitation, Western Blot
Purification Method
This monoclonal antibody was purified using Protein A
Concentration
1.0 - 5.0 mg/mL
Endotoxin
≤ 0.5 EU/mg as determined by the LAL method
Purity
>98% by SDS-PAGE and HPLC
Buffer
ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions
Blue ice
Storage Conditions
This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution
The CD54 antigen is a membrane glycoprotein with a wide tissue distribution that includes vascular endothelium and many cells of the immune system. CD54 is weakly expressed on resting peripheral blood lymphocytes. Upon activation by mitogens, the CD54 antigen is strongly expressed on B-cells, T-cells, macrophages and granulocytes. CD54 is the receptor for rhinoviruses and malaria.
Aggregation
Aggregation level ≤ 1%
Applications Notes
Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control
https://www.ichor.bio/product/Mouse-IgG1-Isotype-Control-for-In-Vivo-Low-Endotoxin-HKSP-ICH2247

Frequently Asked Questions

What is the catalog number for Anti-ICAM-1 (15.2) In Vivo Antibody - Ultra-Low Endotoxin?

The catalog number for Anti-ICAM-1 (15.2) In Vivo Antibody - Ultra-Low Endotoxin is ICH1027UL-5mg.

What sizes are available for Anti-ICAM-1 (15.2) In Vivo Antibody - Ultra-Low Endotoxin?

Anti-ICAM-1 (15.2) In Vivo Antibody - Ultra-Low Endotoxin is available in the following size(s): 5 mg.

Is Anti-ICAM-1 (15.2) In Vivo Antibody - Ultra-Low Endotoxin in stock?

Anti-ICAM-1 (15.2) In Vivo Antibody - Ultra-Low Endotoxin is currently made to order / not held in immediate stock. Contact us for lead time.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

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