Bulk Anti-Human CD119 (GIR 208) Antibody

Catalog number ICH1028-100mg

Price for ICH1028-100mg

Size / count 100 mg

Specifications

Catalog number: ICH1028-100mg
Size / count: 100 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Interferon-gamma (IFN-gamma) exerts its biologic effects by interacting with a single high affinity receptor, IFN-gamma receptor. This receptor is present on almost all cell types except mature erythrocytes. The IFN-gamma receptor consists of two polypeptide chains alpha and beta and requires association of JAK1, JAK2 and Stat1 for IFN-gamma signal transduction. In signal transduction, IFN-gamma induces tyrosine phosphorylation of IFN-gamma receptor alpha (IFNGR1) leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-gamma induced gene transcription. The IFN-gamma receptor is structurally related to the recently cloned IL-10 receptor. GIR 208 binds IFNGR1 and blocks binding of IFN-gamma to the receptor.
CAS Number: 9007-83-4
Specifications: Anti-CD119 In Vivo Antibody - Low Endotoxin (GIR 208) recognizes Human IFN gamma R alpha
Product Name Alternative: Interferon gamma receptor 1, IFN-gamma receptor 1, IFN-gamma-R1, CDw119, Interferon gamma receptor alpha-chain2, IFN-gamma-R-alpha
UniProt: P15260
Host: Mouse
Species Reactivity: Human
Target: CD119
Isotype: IgG1
Clone: GIR 208
Applications: Immunoprecipitation, Western Blot, ELISA, Neutralization, Flow Cytometry
Purification Method: This monoclonal antibody was purified using Protein A
Concentration: 1.0 - 5.0 mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE and HPLC
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: Anti-CD119 In Vivo Antibody - Low Endotoxin (GIR 208) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution: The IFN-gamma receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.
Aggregation: Aggregation level ≤ 5%
Applications Notes: Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control: https://www.ichor.bio/product/Mouse-IgG1-Isotype-Control-for-In-Vivo-Low-Endotoxin-HKSP-ICH2247

Frequently Asked Questions

What is the catalog number for Bulk Anti-Human CD119 (GIR 208) Antibody?

The catalog number for Bulk Anti-Human CD119 (GIR 208) Antibody is ICH1028-100mg.

What sizes are available for Bulk Anti-Human CD119 (GIR 208) Antibody?

Bulk Anti-Human CD119 (GIR 208) Antibody is available in the following size(s): 100 mg.

Is Bulk Anti-Human CD119 (GIR 208) Antibody in stock?

Bulk Anti-Human CD119 (GIR 208) Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.