Anti-Mouse CD11b (M1/70) In Vivo Antibody - Low Endotoxin

Catalog number ICH1049-25mg

Price for ICH1049-25mg

Size / count 25 mg

Specifications

Catalog number: ICH1049-25mg
Size / count: 25 mg
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Specifications: Anti-CD11b In Vivo Antibody - Low Endotoxin (M1/70) recognizes the (Mr 170 kD) alpha m subunit of Mac-1 (CD11b/CD18, alpha m beta 2 integrin), the mouse macrophage-granulocyte specific antigen. Mac-1 is a macrophage differentiation antigen associated with type three complement receptor and mediates adhesion to CD54 (ICAM-1).
Product Name Alternative: Integrin alpha-M, Itgam, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1
UniProt: P05555
Host: Rat
Species Reactivity: Mouse
Target: CD11b
Isotype: IgG2b
Clone: M1/70
Applications: Immunoprecipitation, Western Blot, Functional Assays, Flow Cytometry, IHC (Frozen), CyTOF, Immunocytochemistry
Purification Method: This monoclonal antibody was purified using Protein G
Concentration: 0.5 mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE and HPLC
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: Anti-CD11b In Vivo Antibody - Low Endotoxin (M1/70) is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution: The Mac-1 CD11b antigen is present on macrophages, granulocytes, natural killer cells, blood monocytes. CD11b is expressed on 8% spleen cells, 44% bone marrow cells and less than 1% of thymocytes.
Aggregation: Aggregation level ≤ 5%
Applications Notes: Functional Assay: Activation of mouse peritoneal macrophages Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control: https://www.ichor.bio/product/Rat-IgG2b-In-Vivo-Isotype-Control-Low-Endotoxin-1-2-ICH2243

Frequently Asked Questions

What is the catalog number for Anti-Mouse CD11b (M1/70) In Vivo Antibody - Low Endotoxin?

The catalog number for Anti-Mouse CD11b (M1/70) In Vivo Antibody - Low Endotoxin is ICH1049-25mg.

What sizes are available for Anti-Mouse CD11b (M1/70) In Vivo Antibody - Low Endotoxin?

Anti-Mouse CD11b (M1/70) In Vivo Antibody - Low Endotoxin is available in the following size(s): 25 mg.

Is Anti-Mouse CD11b (M1/70) In Vivo Antibody - Low Endotoxin in stock?

Anti-Mouse CD11b (M1/70) In Vivo Antibody - Low Endotoxin is currently made to order / not held in immediate stock. Contact us for lead time.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

All Products