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Product details

Anti-Mouse CD11b (M1/70) In Vivo Antibody - Low Endotoxin

Catalog number ICH1049-50mg

Price for ICH1049-50mg

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Size / count 50 mg

Specifications

Catalog number
ICH1049-50mg
Size / count
50 mg
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Specifications
Anti-CD11b In Vivo Antibody - Low Endotoxin (M1/70) recognizes the (Mr 170 kD) alpha m subunit of Mac-1 (CD11b/CD18, alpha m beta 2 integrin), the mouse macrophage-granulocyte specific antigen. Mac-1 is a macrophage differentiation antigen associated with type three complement receptor and mediates adhesion to CD54 (ICAM-1).
Product Name Alternative
Integrin alpha-M, Itgam, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1
UniProt
P05555
Host
Rat
Species Reactivity
Mouse
Target
CD11b
Isotype
IgG2b
Clone
M1/70
Applications
Immunoprecipitation, Western Blot, Functional Assays, Flow Cytometry, IHC (Frozen), CyTOF, Immunocytochemistry
Purification Method
This monoclonal antibody was purified using Protein G
Concentration
0.5 mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Buffer
ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions
Blue ice
Storage Conditions
Anti-CD11b In Vivo Antibody - Low Endotoxin (M1/70) is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution
The Mac-1 CD11b antigen is present on macrophages, granulocytes, natural killer cells, blood monocytes. CD11b is expressed on 8% spleen cells, 44% bone marrow cells and less than 1% of thymocytes.
Aggregation
Aggregation level ≤ 5%
Applications Notes
Functional Assay: Activation of mouse peritoneal macrophages Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control
https://www.ichor.bio/product/Rat-IgG2b-In-Vivo-Isotype-Control-Low-Endotoxin-1-2-ICH2243

Frequently Asked Questions

What is the catalog number for Anti-Mouse CD11b (M1/70) In Vivo Antibody - Low Endotoxin?

The catalog number for Anti-Mouse CD11b (M1/70) In Vivo Antibody - Low Endotoxin is ICH1049-50mg.

What sizes are available for Anti-Mouse CD11b (M1/70) In Vivo Antibody - Low Endotoxin?

Anti-Mouse CD11b (M1/70) In Vivo Antibody - Low Endotoxin is available in the following size(s): 50 mg.

Is Anti-Mouse CD11b (M1/70) In Vivo Antibody - Low Endotoxin in stock?

Anti-Mouse CD11b (M1/70) In Vivo Antibody - Low Endotoxin is currently made to order / not held in immediate stock. Contact us for lead time.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

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