- Catalog number
- ICH1064-25mg
- Size / count
- 25 mg
- Dry ice
- No
- Hazardous
- No
- Discontinued
- No
- Background
- TCD90 or Thy1 is a 25-35 kDa GPI-anchored protein belonging to the Ig superfamily that is expressed by thymocytes, peripheral T cells, myoblasts, epidermal cells, and keratinocytes. The function of Thy1 is thought to play roles in regulation of cell adhesion, apoptosis, metastasis, inflammation, and fibrosis. Clone T24/31 antibody is useful for depletion of T lymphocytes.
- CAS Number
- 9007-83-4
- Specifications
- Anti-CD90 In Vivo Antibody - Low Endotoxin (T24/31) recognizes a non-polymorphic (Mr 25-30 kD) determinant on the Thy1.1 and Thy1.2 alloantigens.
- Product Name Alternative
- Thy-1, Thy1
- UniProt
- P01831
- Host
- Rat
- Species Reactivity
- Mouse
- Target
- CD90
- Isotype
- IgG2b Kappa
- Clone
- T24/31
- Applications
- Western Blot, Functional Assays, Flow Cytometry
- Purification Method
- This monoclonal antibody was purified using Protein G
- Concentration
- 1.0 - 5.0 mg/mL
- Endotoxin
- ≤ 1.0 EU/mg as determined by the LAL method
- Purity
- >95% by SDS-PAGE and HPLC
- Buffer
- ICH3001-100mL
ICH3002-100mL
ICH3003-100mL
- Shipping Conditions
- Blue ice
- Storage Conditions
- Anti-CD90 In Vivo Antibody - Low Endotoxin (T24/31) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
- Formulation
- 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
- Antigen Distribution
- The CD90 Thy-1 antigen is present on thymocytes, peripheral T-cells and some intraepithelial T-lymphocytes of all mouse strains tested.
- Aggregation
- Aggregation level ≤ 5%
- Applications Notes
- Functional Assay: Anti Thy-1 is mitogenic for resting T-cells and induces IL-2 secretion from normal T-cells and T-cell hybridomas.
Each investigator should determine their own optimal working dilution for specific applications.
- Isotype Control
- https://www.ichor.bio/product/Rat-IgG2b-In-Vivo-Isotype-Control-Low-Endotoxin-1-2-ICH2243