Anti-CD115 (AFS98) In Vivo Antibody - Low Endotoxin

Catalog number ICH1068-100mg

Price for ICH1068-100mg

Size / count 100 mg

Specifications

Catalog number: ICH1068-100mg
Size / count: 100 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Macrophage colony-stimulating factor (M-CSF, also termed CSF-1) receptor is an integral membrane tyrosine kinase, expressed in monocytes (macrophages and their progenitors) and drives growth and development of this blood cell lineage. It also triggers growth and development of mononuclear phagocytes and placental trophoblasts. M-CSF receptor is present in osteoclasts both at mRNA and protein levels. When M-CSF ligand specifically binds to the M-CSF receptor on osteoclasts, it induces receptor dimerization, activation and autophosphorylation of cytoplasmic tyrosine residues M-CSF and its receptor present as candidate therapeutic targets in states of inflammatory bone erosion.
CAS Number: 9007-83-4
Specifications: Anti-CD115 In Vivo Antibody - Low Endotoxin (AFS98) recognizes an epitope on Mouse M-CSFR
Product Name Alternative: Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor (EC:2.7.10.1), CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, Csf1r, Csfmr, Fms
UniProt: P09581
Host: Rat
Species Reactivity: Mouse
Target: CD115
Isotype: IgG2a Kappa
Clone: AFS98
Applications: Western Blot, Blocking, Functional Assays, Flow Cytometry
Purification Method: This monoclonal antibody was purified using Protein G
Concentration: 1.0 - 5.0 mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE and HPLC
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: Anti-CD115 In Vivo Antibody - Low Endotoxin (AFS98) is stable when stored at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. and keep sterile.
Formulation: 0.01 M phosphate buffered saline (PBS), pH 7.2 - 7.4 without azide or BSA.
Antigen Distribution: Monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, osteoclasts
Aggregation: Aggregation level ≤ 5%
Applications Notes: Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control: https://www.ichor.bio/product/Rat-IgG2a-In-Vivo-Isotype-Control-Low-Endotoxin-1-1-ICH2244

Frequently Asked Questions

What is the catalog number for Anti-CD115 (AFS98) In Vivo Antibody - Low Endotoxin?

The catalog number for Anti-CD115 (AFS98) In Vivo Antibody - Low Endotoxin is ICH1068-100mg.

What sizes are available for Anti-CD115 (AFS98) In Vivo Antibody - Low Endotoxin?

Anti-CD115 (AFS98) In Vivo Antibody - Low Endotoxin is available in the following size(s): 100 mg.

Is Anti-CD115 (AFS98) In Vivo Antibody - Low Endotoxin in stock?

Anti-CD115 (AFS98) In Vivo Antibody - Low Endotoxin is currently made to order / not held in immediate stock. Contact us for lead time.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.