Anti-CD115 (AFS98) In Vivo Antibody - Low Endotoxin

Catalog number ICH1068-50mg

Price for ICH1068-50mg

Size / count 50 mg

Specifications

Catalog number: ICH1068-50mg
Size / count: 50 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Macrophage colony-stimulating factor (M-CSF, also termed CSF-1) receptor is an integral membrane tyrosine kinase, expressed in monocytes (macrophages and their progenitors) and drives growth and development of this blood cell lineage. It also triggers growth and development of mononuclear phagocytes and placental trophoblasts. M-CSF receptor is present in osteoclasts both at mRNA and protein levels. When M-CSF ligand specifically binds to the M-CSF receptor on osteoclasts, it induces receptor dimerization, activation and autophosphorylation of cytoplasmic tyrosine residues M-CSF and its receptor present as candidate therapeutic targets in states of inflammatory bone erosion.
CAS Number: 9007-83-4
Specifications: Anti-CD115 In Vivo Antibody - Low Endotoxin (AFS98) recognizes an epitope on Mouse M-CSFR
Product Name Alternative: Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor (EC:2.7.10.1), CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, Csf1r, Csfmr, Fms
UniProt: P09581
Host: Rat
Species Reactivity: Mouse
Target: CD115
Isotype: IgG2a Kappa
Clone: AFS98
Applications: Western Blot, Blocking, Functional Assays, Flow Cytometry
Purification Method: This monoclonal antibody was purified using Protein G
Concentration: 1.0 - 5.0 mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE and HPLC
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: Anti-CD115 In Vivo Antibody - Low Endotoxin (AFS98) is stable when stored at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles. and keep sterile.
Formulation: 0.01 M phosphate buffered saline (PBS), pH 7.2 - 7.4 without azide or BSA.
Antigen Distribution: Monocytes/macrophages, peritoneal exudate cells, plasmacytoid and conventional dendritic cells, osteoclasts
Aggregation: Aggregation level ≤ 5%
Applications Notes: Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control: https://www.ichor.bio/product/Rat-IgG2a-In-Vivo-Isotype-Control-Low-Endotoxin-1-1-ICH2244

Frequently Asked Questions

What is the catalog number for Anti-CD115 (AFS98) In Vivo Antibody - Low Endotoxin?

The catalog number for Anti-CD115 (AFS98) In Vivo Antibody - Low Endotoxin is ICH1068-50mg.

What sizes are available for Anti-CD115 (AFS98) In Vivo Antibody - Low Endotoxin?

Anti-CD115 (AFS98) In Vivo Antibody - Low Endotoxin is available in the following size(s): 50 mg.

Is Anti-CD115 (AFS98) In Vivo Antibody - Low Endotoxin in stock?

Anti-CD115 (AFS98) In Vivo Antibody - Low Endotoxin is currently made to order / not held in immediate stock. Contact us for lead time.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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