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Product details

Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin

Catalog number ICH1069-100mg

Price for ICH1069-100mg

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Size / count 100 mg

Specifications

Catalog number
ICH1069-100mg
Size / count
100 mg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-A and TNF-B (also known as LT-A). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-ĸB induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding.
CAS Number
9007-83-4
Specifications
Armenian Hamster anti-Mouse CD120A (Clone 55R-593) recognizes Mouse CD120A
Product Name Alternative
Tumor necrosis factor receptor superfamily member 1A, Tnfrsf1a, TNF-R1, TNF-RI, p55, p60, CD120a
UniProt
P25118
Host
Armenian Hamster
Species Reactivity
Mouse
Target
TNF Receptor I
Isotype
IgG1
Clone
55R-593
Applications
Immunoprecipitation, Western Blot
Purification Method
This monoclonal antibody was purified using Protein A
Concentration
1.0 mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Buffer
ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions
Blue ice
Storage Conditions
This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C.
Formulation
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution
Variety of cell types at low levels
Aggregation
Aggregation level ≤ 5%
Applications Notes
Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control
https://www.ichor.bio/product/Armenian-Hamster-IgG-Isotype-Control-for-In-Vivo-Low-Endotoxin-PIP-ICH2251

Frequently Asked Questions

What is the catalog number for Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin?

The catalog number for Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin is ICH1069-100mg.

What sizes are available for Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin?

Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin is available in the following size(s): 100 mg.

Is Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin in stock?

Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin is currently made to order / not held in immediate stock. Contact us for lead time.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

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