Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin

Catalog number ICH1069-25mg

Price for ICH1069-25mg

Size / count 25 mg

Specifications

Catalog number: ICH1069-25mg
Size / count: 25 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-A and TNF-B (also known as LT-A). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-ĸB induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding.
CAS Number: 9007-83-4
Specifications: Armenian Hamster anti-Mouse CD120A (Clone 55R-593) recognizes Mouse CD120A
Product Name Alternative: Tumor necrosis factor receptor superfamily member 1A, Tnfrsf1a, TNF-R1, TNF-RI, p55, p60, CD120a
UniProt: P25118
Host: Armenian Hamster
Species Reactivity: Mouse
Target: TNF Receptor I
Isotype: IgG1
Clone: 55R-593
Applications: Immunoprecipitation, Western Blot
Purification Method: This monoclonal antibody was purified using Protein A
Concentration: 1.0 mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE and HPLC
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C.
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution: Variety of cell types at low levels
Aggregation: Aggregation level ≤ 5%
Applications Notes: Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control: https://www.ichor.bio/product/Armenian-Hamster-IgG-Isotype-Control-for-In-Vivo-Low-Endotoxin-PIP-ICH2251

Frequently Asked Questions

What is the catalog number for Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin?

The catalog number for Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin is ICH1069-25mg.

What sizes are available for Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin?

Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin is available in the following size(s): 25 mg.

Is Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin in stock?

Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin is currently made to order / not held in immediate stock. Contact us for lead time.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.