Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin

Catalog number ICH1069-50mg

Price for ICH1069-50mg

Size / count 50 mg

Specifications

Catalog number: ICH1069-50mg
Size / count: 50 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-A and TNF-B (also known as LT-A). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-ĸB induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding.
CAS Number: 9007-83-4
Specifications: Armenian Hamster anti-Mouse CD120A (Clone 55R-593) recognizes Mouse CD120A
Product Name Alternative: Tumor necrosis factor receptor superfamily member 1A, Tnfrsf1a, TNF-R1, TNF-RI, p55, p60, CD120a
UniProt: P25118
Host: Armenian Hamster
Species Reactivity: Mouse
Target: TNF Receptor I
Isotype: IgG1
Clone: 55R-593
Applications: Immunoprecipitation, Western Blot
Purification Method: This monoclonal antibody was purified using Protein A
Concentration: 1.0 mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE and HPLC
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C.
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution: Variety of cell types at low levels
Aggregation: Aggregation level ≤ 5%
Applications Notes: Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control: https://www.ichor.bio/product/Armenian-Hamster-IgG-Isotype-Control-for-In-Vivo-Low-Endotoxin-PIP-ICH2251

Frequently Asked Questions

What is the catalog number for Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin?

The catalog number for Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin is ICH1069-50mg.

What sizes are available for Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin?

Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin is available in the following size(s): 50 mg.

Is Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin in stock?

Anti-Mouse CD120a (55R-593) In Vivo Antibody - Low Endotoxin is currently made to order / not held in immediate stock. Contact us for lead time.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.