Anti-CTLA-4 (9H10) In Vivo Antibody - Low Endotoxin

Catalog number ICH1084-5mg

Price for ICH1084-5mg

Size / count 5 mg

Specifications

Catalog number: ICH1084-5mg
Size / count: 5 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) also known as CD152, is a protein which is expressed on the surface of Helper T cells and plays an important regulatory role in the immune system. CTLA4 is a member of the immunoglobulin superfamily, expressed on the surface of Helper T cells. CTLA4 transmits an inhibitory signal to T cells. CTLA4 is potentially therapeutic in auto-immune diseases4, such as rheumatoid arthritis, HIV, autoimmune thyroid disease, multiple sclerosis and may also be useful during organ transplantation and cancer treatment. Clone 9H10 antibody has been shown to promote T cell co-stimulation by blocking CTLA4 binding, allowing for CD28 binding.
CAS Number: 9007-83-4
Specifications: Anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) recognizes an epitope on Mouse CTLA-4
Product Name Alternative: Ctla4, Cytotoxic T-lymphocyte protein 4, CD152
UniProt: P09793
Host: Syrian Hamster
Species Reactivity: Mouse
Target: CTLA-4
Isotype: IgG
Clone: 9H10
Applications: Western Blot, Blocking, ELISA, Flow Cytometry
Purification Method: This monoclonal antibody was purified using Protein A
Concentration: 1.0 - 5.0 mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE and HPLC
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: Anti-CTLA-4 In Vivo Antibody - Low Endotoxin (9H10) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution: Activated T cells
Aggregation: Aggregation level ≤ 5%
Applications Notes: Each investigator should determine their own optimal working dilution for specific applications.

Frequently Asked Questions

What is the catalog number for Anti-CTLA-4 (9H10) In Vivo Antibody - Low Endotoxin?

The catalog number for Anti-CTLA-4 (9H10) In Vivo Antibody - Low Endotoxin is ICH1084-5mg.

What sizes are available for Anti-CTLA-4 (9H10) In Vivo Antibody - Low Endotoxin?

Anti-CTLA-4 (9H10) In Vivo Antibody - Low Endotoxin is available in the following size(s): 5 mg.

Is Anti-CTLA-4 (9H10) In Vivo Antibody - Low Endotoxin in stock?

Anti-CTLA-4 (9H10) In Vivo Antibody - Low Endotoxin is currently made to order / not held in immediate stock. Contact us for lead time.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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