Anti-Mouse CTLA-4 (UC10-4F10-11) In Vivo Antibody - Low Endotoxin

Catalog number ICH1085-100mg

Price for ICH1085-100mg

Size / count 100 mg

Specifications

Catalog number: ICH1085-100mg
Size / count: 100 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: CD152, also known as CTLA-4 or Ly-56 has significant similarity to CD28 in amino acid sequence, structure, and genomic organization. Furthermore, CD152 and CD28 share common B7 family counter-receptors. Unlike CD28, CD152 expression appears to be restricted to activated T cells and CD25+CD4+ regulatory T (Treg) cells. CD152 is thought to play a role in the induction and maintenance of immunological tolerance as well as the development of protective immunity and thymocyte regulation.
CAS Number: 9007-83-4
Specifications: Anti-CTLA-4 In Vivo Antibody - Low Endotoxin (UC10-4F10-11) recognizes an epitope on Mouse CD152
Product Name Alternative: Ctla4, Cytotoxic T-lymphocyte protein 4, CD152
UniProt: P09793
Host: Armenian Hamster
Species Reactivity: Mouse
Target: CTLA-4
Isotype: IgG1 Kappa
Clone: UC10-4F10-11
Applications: Flow Cytometry, Western Blot, Functional Assays, Immunoprecipitation
Purification Method: This monoclonal antibody was purified using Protein A
Concentration: ≥ 2.0 mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE and HPLC
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: Anti-CTLA-4 In Vivo Antibody - Low Endotoxin (UC10-4F10-11) is stable when stored at 2-8°C. Do not freeze.
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.4, without BSA or sodium azide added.
Antigen Distribution: The UC10-4F10-11 antibody reacts with CD152 (CTLA-4), which is expressed on activated T lymphocytes 2-3 days after stimulation through T cell receptor.
Aggregation: Aggregation level ≤ 5%
Applications Notes: Functional Assay: Clone UC10-4F10-11 antibody has been shown to promote T cell co-stimulation by blocking CTLA-4 binding to the B7 co-receptors, allowing for CD28 binding. Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control: https://www.ichor.bio/product/Armenian-Hamster-IgG-Isotype-Control-for-In-Vivo-Low-Endotoxin-PIP-ICH2251

Frequently Asked Questions

What is the catalog number for Anti-Mouse CTLA-4 (UC10-4F10-11) In Vivo Antibody - Low Endotoxin?

The catalog number for Anti-Mouse CTLA-4 (UC10-4F10-11) In Vivo Antibody - Low Endotoxin is ICH1085-100mg.

What sizes are available for Anti-Mouse CTLA-4 (UC10-4F10-11) In Vivo Antibody - Low Endotoxin?

Anti-Mouse CTLA-4 (UC10-4F10-11) In Vivo Antibody - Low Endotoxin is available in the following size(s): 100 mg.

Is Anti-Mouse CTLA-4 (UC10-4F10-11) In Vivo Antibody - Low Endotoxin in stock?

Anti-Mouse CTLA-4 (UC10-4F10-11) In Vivo Antibody - Low Endotoxin is currently made to order / not held in immediate stock. Contact us for lead time.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

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