Anti-Mouse IL-1b (B122) In Vivo Antibody - Low Endotoxin

Catalog number ICH1100-50mg

Price for ICH1100-50mg

Size / count 50 mg

Specifications

Catalog number: ICH1100-50mg
Size / count: 50 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Interleukin 1 beta (IL1 beta) is a proinflammatory cytokine belonging to IL1 family that is synthesized as a precursor. The IL1 beta precursor form is not biologically active. It is expressed mainly by stimulated macrophages and monocytes. IL1 beta is known to be a mediator in inflammatory response and to be involved in a variety of cellular activities, proliferation, differentiation and apoptosis. It has been recently found that IL1 beta is a major cause of severe inflammation in the mouse model of Crohns disease which makes IL1 beta an important target for this disease. The B122 antibody has been reported to neutralize the bioactivity of natural or recombinant IL-1β.
CAS Number: 9007-83-4
Specifications: Anti-IL-1b In Vivo Antibody - Low Endotoxin (B122) recognizes Mouse IL-1B
Product Name Alternative: Interleukin-1 beta, IL-1B
UniProt: P10749
Host: Armenian Hamster
Species Reactivity: Mouse
Target: IL-1b
Isotype: IgG
Clone: B122
Applications: Neutralization, Immunoprecipitation, Western Blot, ELISA
Purification Method: This monoclonal antibody was purified using Protein A
Concentration: 1.0 mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE and HPLC
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: Anti-IL-1b In Vivo Antibody - Low Endotoxin (B122) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution: Monocytes, tissue macrophages, Langerhan cells, dendritic cells, T lymphocytes, B lymphocytes, natural killer (NK) cells and many other B cells, T cells, related monocytes
Aggregation: Aggregation level ≤ 5%
Applications Notes: Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control: https://www.ichor.bio/product/Armenian-Hamster-IgG-Isotype-Control-for-In-Vivo-Low-Endotoxin-PIP-ICH2251

Frequently Asked Questions

What is the catalog number for Anti-Mouse IL-1b (B122) In Vivo Antibody - Low Endotoxin?

The catalog number for Anti-Mouse IL-1b (B122) In Vivo Antibody - Low Endotoxin is ICH1100-50mg.

What sizes are available for Anti-Mouse IL-1b (B122) In Vivo Antibody - Low Endotoxin?

Anti-Mouse IL-1b (B122) In Vivo Antibody - Low Endotoxin is available in the following size(s): 50 mg.

Is Anti-Mouse IL-1b (B122) In Vivo Antibody - Low Endotoxin in stock?

Anti-Mouse IL-1b (B122) In Vivo Antibody - Low Endotoxin is currently made to order / not held in immediate stock. Contact us for lead time.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.